ID K9F9F5_PEND2 Unreviewed; 441 AA.
AC K9F9F5;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Transcription factor iws1 {ECO:0000313|EMBL:EKV06070.1};
GN ORFNames=PDIG_78480 {ECO:0000313|EMBL:EKV06070.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV06070.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV06070.1}.
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DR EMBL; AKCT01000295; EKV06070.1; -; Genomic_DNA.
DR AlphaFoldDB; K9F9F5; -.
DR STRING; 1170229.K9F9F5; -.
DR eggNOG; KOG1793; Eukaryota.
DR HOGENOM; CLU_045275_1_0_1; -.
DR InParanoid; K9F9F5; -.
DR OMA; RNNVQHA; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000009882}.
FT DOMAIN 265..342
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..84
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 441 AA; 50454 MW; 6130FC75D2A1C7F7 CRC64;
MSASPDRKAV TLATSPEPEV PEQVASPVAG DDNEGKNFAE STAEAKEVTE DIDDELNVAD
DDEADDKLSD DESILSEVDE AQFDNFDPEN VNVEDRPQLA IDEDNLKLIG RHKRKRTEDG
ETRPRRKEGR REKKSRRADE GGDEGGSSRR RERKKREDKP DTDEETLDPE TRRRRALDRA
MDEAMKKPAK RRFRKQDGID LESMADAEIE DMRKRMTHAA QMDAINRQEG KPAMHKLKLL
PEVIMLLNRN QYTSALVDPE INLLEAVRFF LEPLDDGSMP AYNIQRDLLT AITKLPINKD
ALIASGIGKV VVFYTKSKRT ERRIKEMAEK LLAEWTRPIL QRSDDYSKRV YQEADYDPTK
VVRRSAPTAE EIQAEARARE MLPPRLLNRA RVDRTNVSYT VVPRQTAVRE TPFARPLGAS
GEDRFRKMQA RQAAARKTSR R
//
