ID K9FQD7_PEND2 Unreviewed; 1247 AA.
AC K9FQD7;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Lipase/esterase family protein {ECO:0000313|EMBL:EKV04948.1};
GN ORFNames=PDIG_86120 {ECO:0000313|EMBL:EKV04948.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV04948.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV04948.1}.
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DR EMBL; AKCT01000316; EKV04948.1; -; Genomic_DNA.
DR AlphaFoldDB; K9FQD7; -.
DR STRING; 1170229.K9FQD7; -.
DR eggNOG; KOG1515; Eukaryota.
DR HOGENOM; CLU_004893_0_1_1; -.
DR InParanoid; K9FQD7; -.
DR OMA; PHWVRTE; -.
DR OrthoDB; 1943592at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR CDD; cd09630; CDH_like_cytochrome; 1.
DR CDD; cd08760; Cyt_b561_FRRS1_like; 1.
DR Gene3D; 1.20.120.1770; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.60.40.1210; Cellobiose dehydrogenase, cytochrome domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR015920; Cellobiose_DH_cyt.
DR InterPro; IPR006593; Cyt_b561/ferric_Rdtase_TM.
DR InterPro; IPR005018; DOMON_domain.
DR InterPro; IPR002168; Lipase_GDXG_HIS_AS.
DR InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR PANTHER; PTHR48081:SF35; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR Pfam; PF07859; Abhydrolase_3; 1.
DR Pfam; PF16010; CDH-cyt; 1.
DR SMART; SM00665; B561; 1.
DR SMART; SM00664; DoH; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF49344; CBD9-like; 1.
DR PROSITE; PS01173; LIPASE_GDXG_HIS; 1.
DR PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1247
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003928700"
FT TRANSMEM 221..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..150
FT /note="DOMON"
FT /evidence="ECO:0000259|SMART:SM00664"
FT DOMAIN 219..341
FT /note="Cytochrome b561"
FT /evidence="ECO:0000259|SMART:SM00665"
FT REGION 846..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1001..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1155..1174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1031
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1087..1102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1212..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1233..1247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10038"
SQ SEQUENCE 1247 AA; 137077 MW; 62F97AC8A889E146 CRC64;
MIRHNFAWLW AIPALAQVQV HSIHPQGHNE ITYSFNVPDN TAKSGSGPIY FQMNSTRQVQ
WFALGQGMQM AGANMFIVYT SGNTVTVSPR SGVGEIEPLY NKDAQIKILH GSGVYDGVIT
ASVRCDTCLK WNGGIENVTS SSSPWIWAVK YGEALNSVSV SEGITQHDDH GVTTIDLKKA
TGGNSVNPFA QMARASISPS EEDPGFAAFR STVKRKKTAH AVLMVLAFVV MFPFFALGLH
IFPSKWTVNV HGTFQLLTLA VVMAGFGLGI SLARQIELID SYHTILGMII VPCLVLFQPA
MGMLQHTFFR KTGRKGPFAY MHRWFGRLMM ILGIINVGLG FKLAQAPRGA VIATSVVAGI
IAMVYIVIYL HRKLLHNKPT VHVTYDEGIQ IIRQFLFYAS KHPVEDLQAF TRQWVPSPHW
VRTETITIPD EFLSSAADAV TKQLGPKGVT RVGGEKWWQW RGPSGELKGE WIEMRNHYNQ
TEGADRHCNR VMLYVHGGAY FFGSVDTHRY MMQRHARKLK GRVFAPEYRL SPQFPFPCGL
HDCMAAYLWL LKSHEPKEII LAGDSAGGGL ALSMLVIMRD QGIPLPAGAI LISPWVDLTH
SFPSIIEDNP GDYIPAYGFR HKPSPAWPPP NADDILEMKN LSRQPTVTAE NVKKAIPQPN
STAEETAIRG YAIHENTPPA AERAYPGQQQ APNPASLHAE PDNIHVVLDG KTVELKDQIQ
LYTTNQLMSH PLVSPVLQPS LGGLPPLQIL TGGGEMLRDE QFYIAHKAAN PTAYPPSDVY
LDEYDPTREI LNKYEPTYVQ LQVWDNLCHV APTLSFTRPA KYMFRAISQF GSWALARAQN
GEVETVDDSA LSAASSNSSE DEDVPGPETA LNSPPGTPGA SCVGKAGDPL PAFHQYMIRQ
RIDKRGHVFP LDPPSFYPVL KIPPAQIGAI NPLLIRMWLD AKKEWDIRFA KEKLRVQSQR
LKELAHGFQD FDGECPPPSS LAARRAAPGV LPKRHAKKNH GMMMWSGWGS RHDERRMEME
TRAEESGRRS TRVSTDAGQA GAWPSTPATN PQIEKTSDQY LTNNKSQSNG YTAVSPDKKE
EFSNGDSSTE RTSTDLETVS RTLSQKSAGP ILILPEVNNN KFTDENASTR ALVHAAGSLP
MKSDLSLAQS KYRPASATGS ATSRSEMLSD TTSTVGGDKD SVAYMNMASD TASTQAVIGA
RGIIAPVTAG ENGCRSTETP SVFSAAGQDS MSHRSEISER EGFKTAD
//
