ID K9GBQ6_PEND2 Unreviewed; 252 AA.
AC K9GBQ6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=PDIG_09060 {ECO:0000313|EMBL:EKV18592.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV18592.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV18592.1}.
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DR EMBL; AKCT01000036; EKV18592.1; -; Genomic_DNA.
DR AlphaFoldDB; K9GBQ6; -.
DR STRING; 1170229.K9GBQ6; -.
DR eggNOG; ENOG502QTD3; Eukaryota.
DR HOGENOM; CLU_070319_0_0_1; -.
DR InParanoid; K9GBQ6; -.
DR OMA; RNEGAVM; -.
DR OrthoDB; 2049468at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0019172; F:glyoxalase III activity; IEA:UniProt.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF22; DJ-1_PFPI DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009882}.
FT DOMAIN 40..191
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 252 AA; 27792 MW; 8F0FD2D2A9FAE281 CRC64;
MHSKKVLIIL SDAHSFSLKR NSGHDAGKVV DQPSGFFLQE LAKPLRKILN AGHKVTFASP
KGLEPAPDPS SESLVANAGN IFERQREWDL IERMKRENGF RSPRPFSTIR DDELTTFAAV
FIPGGHSPLQ DLGGNAELGR ILRYFHRENK PTAVICHGPY ALLSTKKAGD GSFVYNGYKI
TSWSDMEENL METLWGGQVE KVESTLRNEG AVMVEGVREK TGGTTLHREL VSAGNPMAAN
ALGDRFVRMI SV
//
