ID K9IK06_DESRO Unreviewed; 446 AA.
AC K9IK06;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative e3 ubiquitin-protein ligase rnf25 {ECO:0000313|EMBL:JAA47440.1};
OS Desmodus rotundus (Vampire bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC Desmodontinae; Desmodus.
OX NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA47440.1};
RN [1] {ECO:0000313|EMBL:JAA47440.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland {ECO:0000313|EMBL:JAA47440.1};
RA Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA Ribeiro J.M.C.;
RT "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT Desmodus rotundus.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GABZ01006085; JAA47440.1; -; mRNA.
DR AlphaFoldDB; K9IK06; -.
DR OrthoDB; 5405601at2759; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR CDD; cd16470; RING-H2_RNF25; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039133; RNF25.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13198:SF4; E3 UBIQUITIN-PROTEIN LIGASE RNF25; 1.
DR PANTHER; PTHR13198; RING FINGER PROTEIN 25; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00591; RWD; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 18..128
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 135..200
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 266..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49775 MW; D7C843AB6C65EBE6 CRC64;
MATSSSAAAG EEDWVLPSEI EVLESIYLDE LQVVKGNGRS SPWEVYITLY PATAEDQDSQ
YVCFTLVLHV PAKYPNEVPQ ISIRNPRGLS DEQIHKISQA LSQVATAGLG TAMLYELIEK
GKEILTDNNI PHGQCVICLY GFQEHEAFTK TPCYHYFHCH CLARYIQHME HELQAQGQEE
ERQHAATKQK AVGVQCPVCR EPLVYDLASL KAAPEPQQPM ELYQPNAESL RQQEELKRLY
QRQQERGGII DLEAERNRYF ISLQQPPAPL EPESAVDASR GSQPPSALAT ELSTSSTAQP
PQSTPLPMAS QYTCEKIPGT GPNQQRLGET QKAILGRPRA SRGPWRQPER RHLKGGEYSA
PKGTNDTQEV PPPERPSKEP MDLKPEEPHN QGVEGPPPRR TGDCARWGRP KSRTPGSSYP
RLRRGRGAYP AGTRREPFSL ESEDGS
//
