ID K9ISU1_DESRO Unreviewed; 485 AA.
AC K9ISU1;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative abl interactor abi-1 {ECO:0000313|EMBL:JAA52003.1};
DE Flags: Fragment;
OS Desmodus rotundus (Vampire bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC Desmodontinae; Desmodus.
OX NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA52003.1};
RN [1] {ECO:0000313|EMBL:JAA52003.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland {ECO:0000313|EMBL:JAA52003.1};
RA Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA Ribeiro J.M.C.;
RT "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT Desmodus rotundus.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, filopodium
CC {ECO:0000256|ARBA:ARBA00004486}. Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}.
CC -!- SIMILARITY: Belongs to the ABI family. {ECO:0000256|ARBA:ARBA00010020}.
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DR EMBL; GABZ01001522; JAA52003.1; -; mRNA.
DR AlphaFoldDB; K9ISU1; -.
DR GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR CDD; cd11971; SH3_Abi1; 1.
DR Gene3D; 6.10.140.1620; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR028457; ABI.
DR InterPro; IPR035725; Abi1_SH3.
DR InterPro; IPR012849; Abl-interactor_HHR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR10460:SF2; ABL INTERACTOR 1; 1.
DR PANTHER; PTHR10460; ABL INTERACTOR FAMILY MEMBER; 1.
DR Pfam; PF07815; Abi_HHR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 2: Evidence at transcript level;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 54..116
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 423..482
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 159..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..396
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAA52003.1"
SQ SEQUENCE 485 AA; 52828 MW; C64120A8B8E48F7B CRC64;
RGSDAEGWKM AELQMLLEEE IPSGKRALIE SYQNLTRVAD YCENNYIQAT DKRKALEETK
AYTTQSLASV AYQINALANN VLQLLDIQAS QLRRMESSIN HISQTVDIHK EKVARREIGI
LTTNKNTSRT HKIIAPANME RPVRYIRKPI DYTVLDDVGH GVKHGNNQPA RTGTLSRTNP
PTQKPPSPPM SGRGTLGRNT PYKTLEPVKP PTVPNDYMTS PARLGSQHSP GRTASLNQRP
RTHSGSSGGS GSRENSGSSS IGIPIAVPTP SPPTIGPAAP GSAPGSQYGT MTRQISRHNS
TTSSTSSGGY RRTPSVTAQF SAQPHVNGGP LYSQNSISIA PPPPPMPQLT PQIPLTGFVA
RVQENIADSP TPPPPPPPDD IPMFDDSPPP PPPPPVDYED EEAAVVQYND PYADGDPAWA
PKNYIEKVVA IYDYTKDKDD ELSFMEGAII YVIKKNDDGW YEGVCNRVTG LFPGNYVESI
MHYTD
//
