ID K9J1N4_DESRO Unreviewed; 534 AA.
AC K9J1N4;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein 2 {ECO:0000256|ARBA:ARBA00039244};
DE AltName: Full=Zinc finger protein 289 {ECO:0000256|ARBA:ARBA00043100};
OS Desmodus rotundus (Vampire bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC Desmodontinae; Desmodus.
OX NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA48059.1};
RN [1] {ECO:0000313|EMBL:JAA48059.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland {ECO:0000313|EMBL:JAA48059.1};
RA Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA Ribeiro J.M.C.;
RT "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT Desmodus rotundus.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}.
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DR EMBL; GABZ01005466; JAA48059.1; -; mRNA.
DR AlphaFoldDB; K9J1N4; -.
DR OrthoDB; 389572at2759; -.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd09029; ArfGap_ArfGap2; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR PANTHER; PTHR45686:SF10; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 11..117
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 137..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 284..318
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 157..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 58084 MW; FA9AD9352C23781C CRC64;
MASEPSKTEI QTCFKRLRAI PTNKACFDCG AKNPSWASIT YGVFLCIDCS GVHRSLGVHL
SFIRSTELDS NWSWFQLRCM QVGGNANATA FFRQHGCTAS DANTKYNSRA AQMYREKIRQ
LGSAALARHG TDLWIDNTSG ASSHSPEKKD SDFFTEHTQP PAWNVPATDV AETQQPAPSA
ESSGLAQTEL GPNTDLLGTS PKASLESMYL SPKGALPARE MKTSLIGKKK PAAAKKGLGA
KKGLGAQKVS SQSFSEIERQ AQVAEKLREQ QAADAKKQAE ESVVASMRLA YQELQIDRKK
EEKKLQNLEG KKREQAERLG MGLVSRSSIS HSVLSEMQVI EQETPVSAKP SRSQLDLFDD
VGTFASGPPK YKDNPFSLGE SFGSRWDTDT TWGVDRMEEK EPEVTISSIR PVSERVTNRR
EVESRSSGLE SSEARQKFAG AKAISSDMFF GREVDTEYEA RSRLQQLSGS SAISSSDLFG
DMDGAHGAGS VSLGNVLPAA DIAQFKQGVK SVAGKMAVLA NGVMNSLQDR YGSY
//
