ID   K9J3S9_DESRO            Unreviewed;      1335 AA.
AC   K9J3S9;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Putative guanine nucleotide binding protein mip1 {ECO:0000313|EMBL:JAA49834.1};
OS   Desmodus rotundus (Vampire bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Phyllostomidae;
OC   Desmodontinae; Desmodus.
OX   NCBI_TaxID=9430 {ECO:0000313|EMBL:JAA49834.1};
RN   [1] {ECO:0000313|EMBL:JAA49834.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Salivary gland {ECO:0000313|EMBL:JAA49834.1};
RA   Francischetti I.M.B., Assumpcao T.C.F., Ma D., Vicente E.C.,
RA   Ribeiro J.M.C.;
RT   "The Vampirome: Transcriptome and Proteome Analysis of the Submandibular
RT   and Accessory Glands of the Vampire Bat and Vector of Human Rabies,
RT   Desmodus rotundus.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC       {ECO:0000256|ARBA:ARBA00009257}.
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DR   EMBL; GABZ01003691; JAA49834.1; -; mRNA.
DR   OrthoDB; 103066at2759; -.
DR   GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR004083; Raptor.
DR   InterPro; IPR029347; Raptor_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   Pfam; PF02985; HEAT; 2.
DR   Pfam; PF14538; Raptor_N; 1.
DR   Pfam; PF00400; WD40; 1.
DR   PRINTS; PR01547; YEAST176DUF.
DR   SMART; SM01302; Raptor_N; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   2: Evidence at transcript level;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          54..207
FT                   /note="Raptor N-terminal CASPase-like"
FT                   /evidence="ECO:0000259|SMART:SM01302"
FT   REGION          853..947
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        853..894
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        924..946
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1335 AA;  148994 MW;  097EC34B8F0B89F0 CRC64;
     MESEMLQSPL LGLGEEDEAD LTDWNLPLAF MKKRHCEKIE GSKSLAQSWR MKDRMKTVSV
     ALVLCLNVGV DPPDVVKTTP CARLECWIDP LSMGPQKALE TIGANLQKQY ENWQPRARYK
     QSLDPTVDEV KKLCTSLRRN AKEERVLFHY NGHGVPRPTV NGEIWVFNKN YTQYIPLSVY
     DLQTWMGSPS IFVYDCSNAG LVVKSFRQFA LQREQELEVA AINPNHPLAQ MPLPPSMKNC
     IQLAACEATE LLPMIPDLPA DLFTSCLTTP IKIALRWFCM QKCVSLVPGV TLDLIEKIPG
     RLNDRRTPLG ELNWIFTAIT DTIAWNVLPR DLFQKLFRQD LLVASLFRNF LLAERIMRSY
     NCTPVSSPRL PPTYMHAMWQ AWDLAVDICL SQLPTIIEEG TAFRHSPFFA EQLTAFQVWL
     TMGVENRSPP EQLPIVLQVL LSQVHRLRAL DLLGRFLDLG PWAVSLALSV GIFPYVLKLL
     QSSARELRPL LVFIWAKILA VDSSCQADLV KDNGHKYFLS VLADPYMPAE HRTMTAFILA
     VIVNSYSTGQ EACLQGNLIA ICLEQLSDPH PLLRQWVAIC LGRIWQNFDS ARWCGVRDSA
     HEKLCSLLSD PIPEVRCAAV FALGTFVGNS AERTDHSTTI DHNVAMMLAQ LISDGSPMVR
     KELVVALTHL VVQYESNFCS VALQFMEEEK NYPLPSPATT EGGSLTPVRD SPCTPRLRAV
     SSYGNIRAVT TARSLNKSLQ NLSLTEESGG AVAFSPGNLS ASSSASSTLG SPDAEEYILS
     FETIDKMRRV SSYSALNSLI GVSFNSVYTQ IWRVLLHLAA DPYPDVCDLA MKVLNSIAYK
     ATANARPQRI LSTSSLTQSA PASPTNKGVH MQQAGGSPPT SSASSSSPTS DVAKQPVSRE
     LPAGRLGATG PTGVQYTPHS HQFPRTRKMF DKGPDQTTDD PDDAAGHKSF ISATMQTGFC
     DWSARYFAQP VMKIPEEHDT ESQVRKEREW RFLRNSRVRK QAQQLIQKGI TRLDDQIFLN
     RNPGVPSVVR FHPFTPCVAV ADKDSICFWD WEKGEKLDYF HNGNPRYTRV TAMEYLNGQD
     CSLLLTATDD GAVRVWKNFA DLEKNPEMVT AWQGLSDMLP TTRGAGMVVD WEQETGLLMS
     SGDVRIIRIW DTDREVKVQD IPTGADSCVT SLSCDSHRSL IVAGLGDGSV RVYDRRMALG
     ECRVMTYREH TAWVLKARLQ RRPEGHIVSV SVNGDVRFFD PRMPESVSTM QIVKGLTALD
     IHPQANLIAC GSMNQFTAVY SGSGELINSI KYYDGFMGQR VGAISCLAFH PYWPHLAVGS
     NDYYMSVYSV EKRVR
//