ID   K9K3M8_HORSE            Unreviewed;       311 AA.
AC   K9K3M8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=RNA-binding protein 48 {ECO:0000256|ARBA:ARBA00015189};
DE   Flags: Fragment;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796 {ECO:0000313|EMBL:AEH58592.1};
RN   [1] {ECO:0000313|EMBL:AEH58592.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Waegele B., Farthmann B., Nyakatura G., Heubner D., Mewes H.-W.,
RA   Steinbach F.;
RT   "Analysis of a normalised equine cDNA library using deep sequencing.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As a component of the minor spliceosome, involved in the
CC       splicing of U12-type introns in pre-mRNAs.
CC       {ECO:0000256|ARBA:ARBA00035004}.
CC   -!- SUBUNIT: Component of the minor spliceosome. Within this complex,
CC       interacts with ARMC7 and PRPF8/PRP8. {ECO:0000256|ARBA:ARBA00035022}.
CC   -!- SIMILARITY: Belongs to the RBM48 family.
CC       {ECO:0000256|ARBA:ARBA00006938}.
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DR   EMBL; JL616385; AEH58592.1; -; mRNA.
DR   AlphaFoldDB; K9K3M8; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd12442; RRM_RBM48; 1.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR039599; RBM48.
DR   InterPro; IPR034264; RBM48_RRM.
DR   PANTHER; PTHR20957:SF0; RNA-BINDING PROTEIN 48; 1.
DR   PANTHER; PTHR20957; UNCHARACTERIZED; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE   2: Evidence at transcript level;
FT   REGION          161..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          287..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..185
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..304
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEH58592.1"
SQ   SEQUENCE   311 AA;  35532 MW;  EC9093C4B87B474E CRC64;
     GAMKELVARF ARYGAIEQYN ALDEYPAEDF TEVYLIKFMN LQSARTAKRK MDEQSFFGGL
     LHVCYAPEFE TVEETRKKLQ ERKAYIARTT KNKDHYMTQK KLVTEHKNTK NFRQDFHSET
     SGFCAAAVNT STGNSDPCFP YSCELPLCYF SSKCTCSSGE HVDRASNSSQ DGRNHDETGE
     HCNHKDSLQK MQIKTLKNSV ACPGAQKAIT PSEAVDRFMP RTTQLQERKR RRQDDRKLGT
     FFETSTSSNE VVIGPLLPDI PKVDMHDDSL NTTADLIRKK LKEVISSVPE PPEDKLEDMH
     TSHSVKQRRR I
//