ID K9L4E2_9CAUD Unreviewed; 332 AA.
AC K9L4E2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00035036};
DE EC=2.4.2.12 {ECO:0000256|ARBA:ARBA00035024};
GN ORFNames=phiTE_197 {ECO:0000313|EMBL:AEZ66363.1};
OS Pectobacterium phage phiTE.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Vequintavirinae; Certrevirus; Certrevirus phiTE.
OX NCBI_TaxID=1116482 {ECO:0000313|EMBL:AEZ66363.1, ECO:0000313|Proteomes:UP000010999};
RN [1] {ECO:0000313|Proteomes:UP000010999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Blower T.R., Evans T.J., Przybilski R., Fineran P.C., Salmond G.P.C.;
RT "Escape from toxin-antitoxin mediated abortive infection can occur by
RT recombination within a generalized transducing phage of Pectobacterium
RT atrosepticum.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEZ66363.1, ECO:0000313|Proteomes:UP000010999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23109916; DOI=10.1371/journal.pgen.1003023;
RA Blower T.R., Evans T.J., Przybilski R., Fineran P.C., Salmond G.P.;
RT "Viral evasion of a bacterial suicide system by RNA-based molecular mimicry
RT enables infectious altruism.";
RL PLoS Genet. 8:E1003023-E1003023(2012).
CC -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-
CC ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and
CC nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00035007}.
CC -!- SIMILARITY: Belongs to the NAPRTase family.
CC {ECO:0000256|ARBA:ARBA00010897}.
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DR EMBL; JQ015307; AEZ66363.1; -; Genomic_DNA.
DR RefSeq; YP_007392659.1; NC_020201.1.
DR GeneID; 14515392; -.
DR KEGG; vg:14515392; -.
DR OrthoDB; 5829at10239; -.
DR Proteomes; UP000010999; Genome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR041525; N/Namide_PRibTrfase.
DR InterPro; IPR016471; Nicotinamide_PRibTrfase.
DR InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR PANTHER; PTHR43816; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43816:SF1; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR Pfam; PF04095; NAPRTase; 1.
DR SUPFAM; SSF51690; Nicotinate/Quinolinate PRTase C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Reference proteome {ECO:0000313|Proteomes:UP000010999};
KW Transferase {ECO:0000313|EMBL:AEZ66363.1}.
FT DOMAIN 172..310
FT /note="Nicotinate/nicotinamide phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04095"
SQ SEQUENCE 332 AA; 37490 MW; F9C0574140306A7D CRC64;
MKNLTLDQKR LVAEKIFLSD YITKKFPKGF VSYVADSYSY WDVLTKLVPS LKDEIMARDG
RVVFRPDSGV PEDIICGTLD WRKVEDLDEA GSLERAAEWA LESAEEEVRE DTPHGECGDE
SVERYFLFGG DLYLMKGELD WNRYDKQYYY IDGSRVLSYD KPELTNEQKG SVELLYEVFG
GEVNSKGYRT LDTHIGLIYG DSITVARAKE IFERLEAKGF ASSNIVFGVG SYTTQYNTRD
SLGMAVKATG AVIDGQQIMV VKEPKTDLGK KSAQGFLKVV RGEDGELKLV DNLSLEQVNV
ADNELRVVFR DGKLLVDETL TEIRERVTAN LK
//
