ID   K9NUU6_9PRIM            Unreviewed;       413 AA.
AC   K9NUU6;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=von Willebrand factor {ECO:0000256|ARBA:ARBA00016619};
DE   Flags: Fragment;
GN   Name=vWF {ECO:0000313|EMBL:AFY23787.1};
OS   Cercopithecus albogularis (Sykes' monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Cercopithecus.
OX   NCBI_TaxID=867370 {ECO:0000313|EMBL:AFY23787.1};
RN   [1] {ECO:0000313|EMBL:AFY23787.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23166696; DOI=10.1371/journal.pone.0049521;
RA   Springer M.S., Meredith R.W., Gatesy J., Emerling C.A., Park J.,
RA   Rabosky D.L., Stadler T., Steiner C., Ryder O.A., Janecka J.E.,
RA   Fisher C.A., Murphy W.J.;
RT   "Macroevolutionary dynamics and historical biogeography of primate
RT   diversification inferred from a species supermatrix.";
RL   PLoS ONE 7:E49521-E49521(2012).
CC   -!- SUBUNIT: Multimeric. Interacts with F8.
CC       {ECO:0000256|ARBA:ARBA00025858}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   EMBL; JX856257; AFY23787.1; -; Genomic_DNA.
DR   AlphaFoldDB; K9NUU6; -.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   CDD; cd01450; vWFA_subfamily_ECM; 2.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR032361; VWA_N2.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR   PANTHER; PTHR24020:SF84; COLLAGEN ALPHA-1(XXI) CHAIN-LIKE ISOFORM X1; 1.
DR   Pfam; PF00092; VWA; 2.
DR   Pfam; PF16164; VWA_N2; 1.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF53300; vWA-like; 2.
DR   PROSITE; PS50234; VWFA; 2.
PE   4: Predicted;
KW   Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          40..216
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          261..413
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFY23787.1"
FT   NON_TER         413
FT                   /evidence="ECO:0000313|EMBL:AFY23787.1"
SQ   SEQUENCE   413 AA;  46006 MW;  7DB8470AEA9DD980 CRC64;
     EEPGGLVVPP TDAPVSPTTP YVEDISEPPL HDFYCSRLLD LVFLLDGSSR LSEAEFEVLK
     AFVVDMMERL RISQKWVRVA VVEYHDGSHA YIGLKDRKRP SELRRIASQV KYAGSQVAST
     SEVLKYTLFQ IFGKIDRPEA SRIALLLMAS QEPQRMSRNF VRYVQGLKKK KVIVIPVGIG
     PHANLKQIRL VEKQSPENKA FVLSGVDELE QQRDEIVSYL CDLAPEAPPP TLPPDMAQVT
     VGPGLLGRST LGPKRNSMVL DVAFVLEGSD KIGEADFNRS KEFMEEVIQR MDVGQDSIHV
     TVLQYSYTVA VEYPFSEAQS KGDILQRVRE IRYQGGNRTN TGLALQYLSE HSFLASQGDR
     EQAPNLVYMV TGNPASDEIK RLPGDIQVVP IGVGPHANVQ ELERIGWPNA PIL
//