ID K9Q9I7_9NOSO Unreviewed; 448 AA.
AC K9Q9I7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:AFY41462.1};
DE EC=1.1.1.22 {ECO:0000313|EMBL:AFY41462.1};
GN ORFNames=Nos7107_0796 {ECO:0000313|EMBL:AFY41462.1};
OS Nostoc sp. PCC 7107.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=317936 {ECO:0000313|EMBL:AFY41462.1, ECO:0000313|Proteomes:UP000010381};
RN [1] {ECO:0000313|EMBL:AFY41462.1, ECO:0000313|Proteomes:UP000010381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7107 {ECO:0000313|EMBL:AFY41462.1,
RC ECO:0000313|Proteomes:UP000010381};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished genome of Nostoc sp. PCC 7107.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP003548; AFY41462.1; -; Genomic_DNA.
DR AlphaFoldDB; K9Q9I7; -.
DR STRING; 317936.Nos7107_0796; -.
DR KEGG; nos:Nos7107_0796; -.
DR PATRIC; fig|317936.3.peg.858; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_2_3; -.
DR InParanoid; K9Q9I7; -.
DR Proteomes; UP000010381; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AFY41462.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010381}.
FT DOMAIN 342..437
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 448 AA; 49608 MW; A7F97B069758450D CRC64;
MIIHRAMLEK PSVLLALQEK IRTHTAIVGV VGLGYVGLPF AVEKAKVGYR VLGIEQNPQR
AEKVNMADNY ITDIKDEDLK QVVTSGNLQA VLNFDRVAEM DVIVICVPTP LTKNLTPNLS
YIESVTHSIA KRLRPGQLVT LESTTYPGTT DEVMRPVLEQ TSGLKQGEDF FLAHSPERVD
PGNQRYTTKN TNKVVGASDT HSLEVATLFY QQTIDHVVPV SSAKAAELVK VFENTFRAVN
IALVNELALL CDRIDLNVWE VLDAANTKPF GIMPFYPGPG VGGHCIPIDP HYLEWKAKEV
NFNTHFIALA GEINRSMPLF VREKARRVLN DLGLAPAKSK ILVIGTAYKK DLGDWRESPS
IMVINYLLED KMTVAYHDPF VPEIEVKGQN FTSLPLTDAN IAAADLVIIA TDHSQVDYVK
LVAKAKAVLD TRGITRHLDC LHDKVTLL
//
