ID K9RL01_9CYAN Unreviewed; 305 AA.
AC K9RL01;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:AFY57944.1};
GN ORFNames=Riv7116_5575 {ECO:0000313|EMBL:AFY57944.1};
OS Rivularia sp. PCC 7116.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Rivulariaceae;
OC Rivularia.
OX NCBI_TaxID=373994 {ECO:0000313|EMBL:AFY57944.1, ECO:0000313|Proteomes:UP000010380};
RN [1] {ECO:0000313|EMBL:AFY57944.1, ECO:0000313|Proteomes:UP000010380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7116 {ECO:0000313|EMBL:AFY57944.1,
RC ECO:0000313|Proteomes:UP000010380};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Szeto E., Ivanova N., Pagani I., Pati A.,
RA Goodwin L., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Kerfeld C.A.;
RT "Finished chromosome of genome of Rivularia sp. PCC 7116.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003549; AFY57944.1; -; Genomic_DNA.
DR AlphaFoldDB; K9RL01; -.
DR STRING; 373994.Riv7116_5575; -.
DR KEGG; riv:Riv7116_5575; -.
DR PATRIC; fig|373994.3.peg.5936; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_0_3_3; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000010380; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000010380}.
FT DOMAIN 20..178
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 184..303
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 190
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 305 AA; 32349 MW; BD89DA58DA3655D8 CRC64;
MQQIYCIHRQ IKLSNMNKQK VTVLGLGAMG SRMGVNLLKA GYSVTVWNRS PKPTEALAAK
GAVVATTPKL AVKEADVVIS MVTDSDASRA VWLDSETGAL SAMRQSAIAI ESSTLTVSWV
KELATEFKHS GIAFLDAPVV GTRPQADSGN LIYLIGGEIE TLKQAENIFL SAGGGKINHA
GEIGKGMAMK LAVNAMFGIQ VAAISEIIGM LIKNGFGLEK AVQYLAELPV TSPAAKNAAN
LILKGNHAAM FPIDLVEKDF RYVMQTAKDV EAASPISEAI HRVYLDAVDK GYGGDNITGV
AKLFV
//
