ID K9SUF4_9SYNE Unreviewed; 523 AA.
AC K9SUF4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AFY73591.1};
GN ORFNames=Syn7502_01523 {ECO:0000313|EMBL:AFY73591.1};
OS Synechococcus sp. PCC 7502.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=1173263 {ECO:0000313|EMBL:AFY73591.1, ECO:0000313|Proteomes:UP000010385};
RN [1] {ECO:0000313|EMBL:AFY73591.1, ECO:0000313|Proteomes:UP000010385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7502 {ECO:0000313|EMBL:AFY73591.1,
RC ECO:0000313|Proteomes:UP000010385};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Synechococcus sp. PCC 7502.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003594; AFY73591.1; -; Genomic_DNA.
DR RefSeq; WP_015168249.1; NC_019702.1.
DR AlphaFoldDB; K9SUF4; -.
DR STRING; 1173263.Syn7502_01523; -.
DR KEGG; synp:Syn7502_01523; -.
DR PATRIC; fig|1173263.3.peg.1585; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_13_3_3; -.
DR OrthoDB; 266524at2; -.
DR Proteomes; UP000010385; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010385};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 470..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 88..124
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 210..368
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 444..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 134..172
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 197..240
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 523 AA; 56325 MW; 28D0C0878AEB85CD CRC64;
MPSSKNAHRF VSVIITSFVI FSAPTKVFAH GGHGDEFKSG DTQPKDAIQV DTNTAKQIGI
KVESVASRQL ELGIKTNGQI EAMPDRKVEI TTPTKGQITQ LLVKLGDRVQ AGQPIAILSS
PEIAELRVAS FEKRAEADGN LREAQANLTL ALQNLDRSQQ IANAEIRQAQ IELKVDRERY
DRDKELLASG AIPSRQVMES ESKLSTARAA LTKAESKLEV LKAEAEVKNA KSALQVAKER
IQLSDSTYNA RLNQLGANAN ADGRIAITSP ITGTVSELKA TLAESGEDAG KPIMTIVNSD
RLLATANIYE KDLNKIKIGQ RVRVTAAGRK FTGKVRTIGA VVNGETRIIP VQAEIENPDR
TLTVGMFAEL EVLTEKSESV VAIPAAAVVE ANGRNLVFVQ NGNAFQPVEV VLGRTSGDFV
EVDNGLFEGD AIATQRATQL YAQSLRGGSK PTESEPKPNE VKESSFSPPV WTMLLTGAIA
GGGIVAGAFW LGRRSGTKMV ILREPELTSD SPLSRDASRR IDR
//
