ID K9T6Z7_9CYAN Unreviewed; 476 AA.
AC K9T6Z7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AFY78208.1};
GN ORFNames=Ple7327_2971 {ECO:0000313|EMBL:AFY78208.1};
OS Pleurocapsa sp. PCC 7327.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pleurocapsales; Hyellaceae;
OC Pleurocapsa.
OX NCBI_TaxID=118163 {ECO:0000313|EMBL:AFY78208.1, ECO:0000313|Proteomes:UP000010382};
RN [1] {ECO:0000313|EMBL:AFY78208.1, ECO:0000313|Proteomes:UP000010382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7327 {ECO:0000313|EMBL:AFY78208.1,
RC ECO:0000313|Proteomes:UP000010382};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Szeto E., Ivanova N., Pagani I., Pati A.,
RA Goodwin L., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Kerfeld C.A.;
RT "Finished genome of Pleurocapsa sp. PCC 7327.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003590; AFY78208.1; -; Genomic_DNA.
DR AlphaFoldDB; K9T6Z7; -.
DR STRING; 118163.Ple7327_2971; -.
DR KEGG; plp:Ple7327_2971; -.
DR PATRIC; fig|118163.3.peg.3306; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_2_3; -.
DR Proteomes; UP000010382; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010382};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..118
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 216..392
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 136..188
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 231..276
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 476 AA; 51871 MW; FAFF710B15F106B6 CRC64;
MEFPLQSKLK NPLLWILGVM TGGILVVGLM TYRMVETPSS EQLLDKLTVP TTRETLAAEI
EASGTVEPIT SVNISPKNPG RLVELRVDQG MRVKRGQILA VMENLEIQAQ GYEAQAKFRQ
ALAQFKEAQV RIPGEIAQAK NRLAQAQASL KQAQAKLPKD IKQAQAQLQA AEARFQLAQA
RIQRNEALLK EGAVTQDEYD AVLNDFRTAL ATGMEAQQRF EQAKTTSFPE IDRLKAAVAE
AQVQLQQRQK TAEAELAQLQ AAAEAARAEL ERIKIQYQDT VIRAPFDGVV TQKYATVGAF
VTPTTSASAT ASATSASILA LASGLEVVAK VPEVDIGQLQ LGQPARIVAD AYPDKVFQGQ
VVKIAPEAVV EQNVTSFEVT VRILTGQETL RSKMNVDVDF VGRQLSNALV VPTVAIVTQE
GQTGVMVPDD NQKPKFKPVT IGLVLNDKTQ ILDGLTPGER VFVDLPENKD QKEIEK
//
