ID K9TCP9_9CYAN Unreviewed; 1665 AA.
AC K9TCP9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Polyketide synthase family protein {ECO:0000313|EMBL:AFY80290.1};
GN ORFNames=Oscil6304_0544 {ECO:0000313|EMBL:AFY80290.1};
OS Oscillatoria acuminata PCC 6304.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=56110 {ECO:0000313|EMBL:AFY80290.1, ECO:0000313|Proteomes:UP000010367};
RN [1] {ECO:0000313|EMBL:AFY80290.1, ECO:0000313|Proteomes:UP000010367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6304 {ECO:0000313|EMBL:AFY80290.1,
RC ECO:0000313|Proteomes:UP000010367};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria acuminata PCC 6304.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003607; AFY80290.1; -; Genomic_DNA.
DR RefSeq; WP_015146940.1; NC_019693.1.
DR STRING; 56110.Oscil6304_0544; -.
DR KEGG; oac:Oscil6304_0544; -.
DR PATRIC; fig|56110.3.peg.651; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_16_6_3; -.
DR InParanoid; K9TCP9; -.
DR OrthoDB; 499075at2; -.
DR Proteomes; UP000010367; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF7; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010367};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 11..440
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1311..1386
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1284..1303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1665 AA; 183246 MW; 8A1F3BA5B76EA566 CRC64;
MDNQNSLDSS VPGIAIIGMT GRFPGAKTLE EFWDNLRNGV ESIAVLSEEE LLASSLAAEQ
VQHPNYVKAK GVLDDVEWFD ASFFGLTPKD AEITDPQHRF FLECAWEALE HSGYNPENYP
GLIGVYAGSG GGLKSYLFKN LYLNPQIQTC TSEYQLSIAN EKDFLPSKLS YKLKLTGPSV
AVQTACSTSL VAVSMACQSL LTYQCDMALA GGVAMTFPQK EGYLYQPGMI LSPDGHCRAF
DANAKGTVSG NGLGIVVLKR LEEAIADGDF IHAVIRGSAI NNDGGLKVGY TAPSIEGQAE
AIAQAQAVAE VDPETITYIE AHGTGTPLGD PIEIAALTEV FSRHTDKTGF CAVGSVKTNI
GHLDTAAGIA GLIKTVLALK HQQIPPSLHF QQPNPQINFE TSPFYVNATL TDWKTNGTPR
RAGVSSFGIG GTNAHVILEE APVRPRQDPG SSGVGLTPHL LLLSAKTPSA LNRATANLAA
HLRANPEVNL ADVAYTLAVG RKAFPYRRRV VAATVEEAIA RLEAVDSQPV ITPVPDKGDR
PVVFLFSGQG TQYIKMAQEL YHTQPRFQGE IDRCCQLLQP LIGLDLREIL YPPDATVAEA
TTQLKQTAIT QPALFTIEYA LAQLWTSWGI QPVAAIGHSI GEYVAACIAG VFSLEDALSL
VAKRGQLMQQ MPPGSMVAVP LPESELQPFL NSDLSLALIN GPGNCVVSGP VEAVQRCQQQ
LSDRAIECRT LHTSHAFHSP MMEPMLPAFT AAVQQVTLNS PKIPYISNVT GTWITPSQAT
NPDYWAQHLR QTVRFAEGLA TLFKQSDWGL LEVGPGRSLT TLAKRHPNKG KDALILSSLR
HPQDEQSDLN LLFTGLGQLW EAGVAVDWEQ FYAGQQRDRL PLPTYPFERQ RYWIEPENKA
QTQVSIPSPG LTPAIWNAMV QAAQSRSQQG LSEFDNPTYL HKKQQLEALC RAYIHRTVHE
LGAFQQPTEG YTLSQFLEKF EILPQYQQLW ARCLNGLVDQ GQLQQQGEQF IQLVPYSPES
FQALLAQVRD LWADTPDYLQ LVECCGDRYA AILTGTEDPL NLLFTGPNAE TLQRVYQNSP
ESHYYVGIMA ATLQALVKSW PSDRTLRILE VGGGTGSATM YLLKELPEDR TSYRFTDVGL
LFIKQAEQKF KDYPFVEYQR LDLDQDPMTQ GYTPESFDLI IASQVIHATR HLSQTLERVR
TLLAPGGFLM MWEGTNPRDL SFDVAFPLLQ RIEEEELRSL YAFLSLDQWQ QALAKHGFVQ
ATAAPLSQSV SEHILIAQTA GLPQSTPVSP HPSSIPMSPN SPRKTDGAIL LPRNSLEEAI
ASVWQQYLGI ASISIHNDFF ELGGDSLVAV QVLSQLREQF HTELPNHTLL EAPTIAELAE
FMAKLSPTPL EPQSALPSCL VNIQSGSGTQ PLFLIHPAGG HVYIYRDLVR QLDENLSVYG
LQARGLDGKL APLDEIPAMA EYYLDALRQV QPKGPYRIGG ASFGGIVAFE MAQQLQASGE
RVELLTIFDC AGPEQLPAGF EEDEVQILSY LLGVGGNLSI SCDRLRQLEP EDRFRYFLAQ
GRDSIRLPSD FGLQELQHYL EMFKRNVRAM RRYHLRPYPG RIVFFRASDR DEISPGDPER
AWLELATDGV EIYEVPGNHI TMNFAPHVKA IADPLTIALQ DARSL
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