ID K9TEJ3_9CYAN Unreviewed; 1013 AA.
AC K9TEJ3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN ORFNames=Oscil6304_1096 {ECO:0000313|EMBL:AFY80823.1};
OS Oscillatoria acuminata PCC 6304.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=56110 {ECO:0000313|EMBL:AFY80823.1, ECO:0000313|Proteomes:UP000010367};
RN [1] {ECO:0000313|EMBL:AFY80823.1, ECO:0000313|Proteomes:UP000010367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6304 {ECO:0000313|EMBL:AFY80823.1,
RC ECO:0000313|Proteomes:UP000010367};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria acuminata PCC 6304.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC fragments with terminal 5'-phosphates, ATP is simultaneously
CC hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC -!- SIMILARITY: Belongs to the HsdR family.
CC {ECO:0000256|ARBA:ARBA00008598}.
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DR EMBL; CP003607; AFY80823.1; -; Genomic_DNA.
DR RefSeq; WP_015147473.1; NC_019693.1.
DR AlphaFoldDB; K9TEJ3; -.
DR STRING; 56110.Oscil6304_1096; -.
DR REBASE; 57914; Oac6304ORF1092P.
DR KEGG; oac:Oscil6304_1096; -.
DR PATRIC; fig|56110.3.peg.1316; -.
DR eggNOG; COG0610; Bacteria.
DR HOGENOM; CLU_010804_0_0_3; -.
DR InParanoid; K9TEJ3; -.
DR OrthoDB; 9758243at2; -.
DR Proteomes; UP000010367; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1570.50; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR InterPro; IPR040980; SWI2_SNF2.
DR PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04313; HSDR_N; 1.
DR Pfam; PF18766; SWI2_SNF2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Helicase {ECO:0000313|EMBL:AFY80823.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010367};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 278..532
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|SMART:SM00487"
SQ SEQUENCE 1013 AA; 117039 MW; D56A162694AAC2EB CRC64;
MDSSSVVFPQ SETAFEQVIE DSLLKQGYVK PQTPFNKNLA IFPDIALNFI RQTQPKAWAK
LEALHGENTG NQIITDLCKW MDTYGSLHTL RHGFKCYGRT LRIAYFKAAH SLNSDLESCY
KANQLGITRQ LQYSTRHRNE LDITLSLNGI PIVTIELKNP LTGQTVEHGK QQYRQDRDPH
EIIFEFKRRT LVHFTVDTEE VWMTTRLAGK ATHFLPFNQG DHNGAGNPRD PQGRTYRTAY
LWENILQPDS LLDLLAQFLH LQIEQKYDDR GRKYQKETMI FPRFHQLQTV RKLIAATQEE
GVGHNYLIDH SAGSGKSNTI AWLTHRLVSL HNTENQRVFE SVIVISDRRI LDQQLQDTIY
QFEHRQGVIQ KIDKDSKQLA EALESAVPII VTTLQKFPFV TRQLLKLAEA RNEQGSGRLP
TRRCAVIIDE AHSSQSGDTA TELKGVLGGE TLHQKAREMA QEEGLEHLEE MFLSMAKRSL
QDNLSFFAFT ATPKHKTLKF FGREGEPFHR YTMRQAIEEG FIMDVFKNYT IYTAYFKLLK
DSGNDPHVQR KQAAKSLTHF MRLHPHNIAQ KTQIMVEHFN NFTRHKIGGK AKAMVVTGSR
LEAVRYKQSF DKYIKEKGYD IKSLVAFSGI VNDDKIPDKT YTEEEMNQGI REKELTEKFA
GDDYQVLLVA EKYQTGFDQP LLHTMYVDKR LSGIKAVQTL SRLNRTHPHK EDTFILDFVN
KREEIQEAFQ QFYEGAELGK EAEPGQLYQL KSQLDASGIY LSEEVNRFCT IYFKPKQRQN
PSDHQGMNAA LDPAVDRFRA LYEQDVEEAE LWRRKLTAFR NLYSFLSQII PYQDSDLEQV
YIFLRHLSTK LFRPSNQGQY DFDSEIKLEY YRLQKISEGS IHLKKGETIP QDGSPAVGTA
ILRENSLKLS QLIDVLNNRF GTDFNQADQL FFDQIVEAAV NTEALQQAAQ VNSVNKFGLL
FDKIVESLFV ERVDQNENIF ARYMNDNDFK NVVSGWLLSE VYKRLSDHHN SER
//
