ID K9WHR7_9CYAN Unreviewed; 612 AA.
AC K9WHR7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:AFZ19324.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:AFZ19324.1};
GN ORFNames=Mic7113_3600 {ECO:0000313|EMBL:AFZ19324.1};
OS Allocoleopsis franciscana PCC 7113.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Allocoleopsis; Allocoleopsis franciscana.
OX NCBI_TaxID=1173027 {ECO:0000313|EMBL:AFZ19324.1, ECO:0000313|Proteomes:UP000010471};
RN [1] {ECO:0000313|EMBL:AFZ19324.1, ECO:0000313|Proteomes:UP000010471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7113 {ECO:0000313|EMBL:AFZ19324.1,
RC ECO:0000313|Proteomes:UP000010471};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Szeto E., Ivanova N., Pagani I., Pati A.,
RA Goodwin L., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Kerfeld C.A.;
RT "Finished chromosome of genome of Microcoleus sp. PCC 7113.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; CP003630; AFZ19324.1; -; Genomic_DNA.
DR RefSeq; WP_015183465.1; NC_019738.1.
DR AlphaFoldDB; K9WHR7; -.
DR STRING; 1173027.Mic7113_3600; -.
DR KEGG; mic:Mic7113_3600; -.
DR PATRIC; fig|1173027.3.peg.3962; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_2_3; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000010471; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:AFZ19324.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010471};
KW Transferase {ECO:0000313|EMBL:AFZ19324.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..239
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 272..583
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 520..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 66078 MW; 2BF1F20EF7F3B209 CRC64;
MTVNQPPSLG RKPTPRTVGR NYQSIFVMLF VSIFLVGGMS ARLVYLQLLE GNRNQQLADN
NRIRLIPKQP VRGNIFDRKG RVLASSRLSH AVYIWPLARK KAEWPETLKL VSKILNIPEG
EIEKRLEKAG YNSPSLLRIA RGITPAQITA MEEYSNQLEG VEVDIEAVRD YPNGAMAAHV
LGYTGELNDE ELAKRKSEGY RMGDIVGQMG VEEAFESQLR GEWGGQQVEV DGAGHVLRVL
GQKKAKSGKD VQLTLDLDVQ KAAEKALGEQ KGAIVALNPN TGAVLAMVSR PTFDPNIFST
RITAATWKQL QGKGNPFVNR SMRGFPPAST FKVVTATAGM ESGKYSPSTI LPTFAALQVG
GTAFGEWNHA GFGSIGFVRA LAMSSNTFFG QIGRGAGGPA LIEWARKYGF GQKTGIELSE
EAQGLVADAA WKQKVYKWDW TVGDTVNMSI GQGFTQATPL QVAVMFAVPA NGGYRVKPHL
LKDNEESKSW RQSLNIKPPT LKVIRQGLRE VVAAGTGKAL NVPELPPSAG KSGTAEAPPG
KSHAWFGAYA PADKPEIVVL AFAEHSGGGG GSVAGPMVRE VMEAYFKHNN PGLIPKPKSE
APTSKPKPAA RN
//
