ID KLDC4_PONAB Reviewed; 522 AA.
AC Q5R8W1;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Kelch domain-containing protein 4;
GN Name=KLHDC4;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CR859637; CAH91799.1; -; mRNA.
DR RefSeq; NP_001126046.1; NM_001132574.1.
DR AlphaFoldDB; Q5R8W1; -.
DR SMR; Q5R8W1; -.
DR STRING; 9601.ENSPPYP00000008609; -.
DR GeneID; 100172995; -.
DR KEGG; pon:100172995; -.
DR CTD; 54758; -.
DR eggNOG; KOG1230; Eukaryota.
DR InParanoid; Q5R8W1; -.
DR OrthoDB; 5481217at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR PANTHER; PTHR46063; KELCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46063:SF1; KELCH DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF13415; Kelch_3; 2.
DR Pfam; PF13418; Kelch_4; 1.
DR SUPFAM; SSF117281; Kelch motif; 2.
PE 2: Evidence at transcript level;
KW Kelch repeat; Phosphoprotein; Reference proteome; Repeat.
FT CHAIN 1..522
FT /note="Kelch domain-containing protein 4"
FT /id="PRO_0000286397"
FT REPEAT 77..129
FT /note="Kelch 1"
FT REPEAT 133..187
FT /note="Kelch 2"
FT REPEAT 188..241
FT /note="Kelch 3"
FT REPEAT 243..289
FT /note="Kelch 4"
FT REPEAT 308..361
FT /note="Kelch 5"
FT REPEAT 443..494
FT /note="Kelch 6"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..522
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 413
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8TBB5"
FT MOD_RES 418
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8TBB5"
SQ SEQUENCE 522 AA; 58231 MW; DBDB810B6C5E002A CRC64;
MGKKGKKEKK GRGAEKTAAK MEKKVSKRSR KEEEDLEALI AHFQTLDAKR TQTVEAPCPP
PSPRLNASLS VHPEKDELIL FGGEYFNGQK TFLYNELYVY NIRKDTWTKV DIPSPPPRRC
AHQAVVVPQG GGQLWVFGGE FASPNGEQFY HYKDLWVLHL ATKTWEQVKS TGSPSGRSGH
RMVAWKRQLI LFGGFHESTR DYIYYNDVYT FNLDTFTWSK LSPSGTGPTP RSGCQMSVTP
QGGIIIYGGY SKQRVKKDVD RGTRHSDMFL LKPEDGREDK WVWTRMNPSG VKPTPRSGFS
AAMALNHQTL FFGGVCDEEE EESLAGEFFN DLYFYDATRN RWFEGQLKGP KSEKKKRRRG
RKEESEGGSK LACGGAGTQG PVQVVKEVVA EDGTVVTIKQ VLAAPGSAGQ PRSEDEDSPE
EAGSSAPGPC PRSNAMLAVK HGVLYVYGGM FEAGDRQVTL SDLHCLDLHR MEAWKALVEM
DPETQEWLEE TDSEEDSEEV EGAEGGDEDE DEDSREESGA ED
//
