ID L0ACV6_NATGS Unreviewed; 247 AA.
AC L0ACV6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Bacterio-opsin activator HTH domain-containing protein {ECO:0000313|EMBL:ELY66788.1};
DE SubName: Full=DNA binding protein {ECO:0000313|EMBL:AFZ71728.1};
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:PLK18343.1};
GN OrderedLocusNames=Natgr_0474 {ECO:0000313|EMBL:AFZ71728.1};
GN ORFNames=C490_12265 {ECO:0000313|EMBL:ELY66788.1}, CYV19_18135
GN {ECO:0000313|EMBL:PLK18343.1};
OS Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP
OS 104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronobacterium.
OX NCBI_TaxID=797304 {ECO:0000313|EMBL:AFZ71728.1, ECO:0000313|Proteomes:UP000010468};
RN [1] {ECO:0000313|Proteomes:UP000010468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2
RC {ECO:0000313|Proteomes:UP000010468};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFZ71728.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SP2 {ECO:0000313|EMBL:AFZ71728.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY66788.1, ECO:0000313|Proteomes:UP000011613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:ELY66788.1,
RC ECO:0000313|Proteomes:UP000011613};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:PLK18343.1, ECO:0000313|Proteomes:UP000234484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:PLK18343.1,
RC ECO:0000313|Proteomes:UP000234484};
RC TISSUE=Freeze-dried powder thallus {ECO:0000313|EMBL:PLK18343.1};
RA Jiang L., He B., Kang J., Yu M., Li N., Fang Y., Tang Z., Wu P., Yao P.,
RA Huang J.;
RT "The characterization of oligonucleotides binding to NgAgo.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003377; AFZ71728.1; -; Genomic_DNA.
DR EMBL; AOIC01000087; ELY66788.1; -; Genomic_DNA.
DR EMBL; PKKI01000091; PLK18343.1; -; Genomic_DNA.
DR RefSeq; WP_005580034.1; NZ_PKKI01000091.1.
DR AlphaFoldDB; L0ACV6; -.
DR STRING; 797304.Natgr_0474; -.
DR GeneID; 14207638; -.
DR KEGG; nge:Natgr_0474; -.
DR PATRIC; fig|797304.7.peg.2490; -.
DR eggNOG; arCOG02274; Archaea.
DR HOGENOM; CLU_096714_0_0_2; -.
DR Proteomes; UP000010468; Chromosome.
DR Proteomes; UP000011613; Unassembled WGS sequence.
DR Proteomes; UP000234484; Unassembled WGS sequence.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR Pfam; PF04967; HTH_10; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010468};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 182..231
FT /note="HTH bat-type"
FT /evidence="ECO:0000259|Pfam:PF04967"
SQ SEQUENCE 247 AA; 27771 MW; 471FB97CD9595B49 CRC64;
MREFVFALEY EPGTNPVADV LAAYPDASIR SLSCHVTKDS LWRVDHAEGA DEALEKLEYA
YEHADFFADC LVKDDCGADC DVQVIDRSNG ALVVYTYWDR TDVCTSVPHV ALEELGEGLL
FETYREGRRY RWRIVLGNGA PIHDFFDALG DEVGDCTGME MLRLTELDPD RTAPNVEGTL
PDEQREALHA AVDHGYYETP RQIDLSELAE ELDIPRSTLS YRLRRAEAEL ATAFAATDDS
LEQLARL
//
