ID L0AIR7_NATGS Unreviewed; 222 AA.
AC L0AIR7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Phosphoesterase {ECO:0000313|EMBL:AFZ72960.1, ECO:0000313|EMBL:PLK21816.1};
DE SubName: Full=Phosphodiesterase, MJ0936 family protein {ECO:0000313|EMBL:ELY69892.1};
GN OrderedLocusNames=Natgr_1765 {ECO:0000313|EMBL:AFZ72960.1};
GN ORFNames=C490_07074 {ECO:0000313|EMBL:ELY69892.1}, CYV19_01575
GN {ECO:0000313|EMBL:PLK21816.1};
OS Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP
OS 104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronobacterium.
OX NCBI_TaxID=797304 {ECO:0000313|EMBL:AFZ72960.1, ECO:0000313|Proteomes:UP000010468};
RN [1] {ECO:0000313|EMBL:AFZ72960.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SP2 {ECO:0000313|EMBL:AFZ72960.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000010468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2
RC {ECO:0000313|Proteomes:UP000010468};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY69892.1, ECO:0000313|Proteomes:UP000011613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:ELY69892.1,
RC ECO:0000313|Proteomes:UP000011613};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:PLK21816.1, ECO:0000313|Proteomes:UP000234484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:PLK21816.1,
RC ECO:0000313|Proteomes:UP000234484};
RC TISSUE=Freeze-dried powder thallus {ECO:0000313|EMBL:PLK21816.1};
RA Jiang L., He B., Kang J., Yu M., Li N., Fang Y., Tang Z., Wu P., Yao P.,
RA Huang J.;
RT "The characterization of oligonucleotides binding to NgAgo.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003377; AFZ72960.1; -; Genomic_DNA.
DR EMBL; AOIC01000058; ELY69892.1; -; Genomic_DNA.
DR EMBL; PKKI01000004; PLK21816.1; -; Genomic_DNA.
DR RefSeq; WP_005578295.1; NZ_PKKI01000004.1.
DR AlphaFoldDB; L0AIR7; -.
DR STRING; 797304.Natgr_1765; -.
DR GeneID; 14208929; -.
DR KEGG; nge:Natgr_1765; -.
DR PATRIC; fig|797304.7.peg.1428; -.
DR eggNOG; arCOG01143; Archaea.
DR HOGENOM; CLU_074761_1_1_2; -.
DR Proteomes; UP000010468; Chromosome.
DR Proteomes; UP000011613; Unassembled WGS sequence.
DR Proteomes; UP000234484; Unassembled WGS sequence.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR020935; PdiEstase_YfcE_CS.
DR InterPro; IPR011152; Pesterase_MJ0912.
DR PANTHER; PTHR42850:SF2; BLL5683 PROTEIN; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF12850; Metallophos_2; 1.
DR PIRSF; PIRSF000883; Pesterase_MJ0912; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS01269; UPF0025; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000010468}.
FT DOMAIN 1..186
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
SQ SEQUENCE 222 AA; 24566 MW; 9D13F0D1C368B8DF CRC64;
MKVGLISDVH SNRIALEAVL EDMPPVDELA CAGDVVGYNP WPADCVDELR ERGVATVMGN
HDAAVATETP FRFNGIAQAG VEHAEGELST EQLEWLADLP KERLECDGRL KIVHGHPDDP
DRYSRYTYPE EFSPRMLDDE DVLVLGHTHV QGVEKFAEGI VLNPGSVGQP RDGDPRAGYA
VIDLDAMTVE THRVEYDIET VQETVQEVGL PERIGRRLER GT
//
