GenomeNet

Database: UniProt
Entry: L0AKY3_NATGS
LinkDB: L0AKY3_NATGS
Original site: L0AKY3_NATGS 
ID   L0AKY3_NATGS            Unreviewed;       196 AA.
AC   L0AKY3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Ribonuclease H {ECO:0000313|EMBL:AFZ73700.1, ECO:0000313|EMBL:ELY67660.1};
GN   OrderedLocusNames=Natgr_2543 {ECO:0000313|EMBL:AFZ73700.1};
GN   ORFNames=C490_10837 {ECO:0000313|EMBL:ELY67660.1}, CYV19_14130
GN   {ECO:0000313|EMBL:PLK19568.1};
OS   Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP
OS   104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natronobacterium.
OX   NCBI_TaxID=797304 {ECO:0000313|EMBL:AFZ73700.1, ECO:0000313|Proteomes:UP000010468};
RN   [1] {ECO:0000313|Proteomes:UP000010468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2
RC   {ECO:0000313|Proteomes:UP000010468};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA   Anderson I., Woyke T.;
RT   "Complete sequence of Natronobacterium gregoryi SP2.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AFZ73700.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SP2 {ECO:0000313|EMBL:AFZ73700.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA   Anderson I., Woyke T.;
RT   "Complete sequence of Natronobacterium gregoryi SP2.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ELY67660.1, ECO:0000313|Proteomes:UP000011613}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SP2 {ECO:0000313|EMBL:ELY67660.1,
RC   ECO:0000313|Proteomes:UP000011613};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
RN   [4] {ECO:0000313|EMBL:PLK19568.1, ECO:0000313|Proteomes:UP000234484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SP2 {ECO:0000313|EMBL:PLK19568.1,
RC   ECO:0000313|Proteomes:UP000234484};
RC   TISSUE=Freeze-dried powder thallus {ECO:0000313|EMBL:PLK19568.1};
RA   Jiang L., He B., Kang J., Yu M., Li N., Fang Y., Tang Z., Wu P., Yao P.,
RA   Huang J.;
RT   "The characterization of oligonucleotides binding to NgAgo.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003377; AFZ73700.1; -; Genomic_DNA.
DR   EMBL; AOIC01000078; ELY67660.1; -; Genomic_DNA.
DR   EMBL; PKKI01000046; PLK19568.1; -; Genomic_DNA.
DR   RefSeq; WP_005579691.1; NZ_PKKI01000046.1.
DR   AlphaFoldDB; L0AKY3; -.
DR   STRING; 797304.Natgr_2543; -.
DR   GeneID; 14208409; -.
DR   KEGG; nge:Natgr_2543; -.
DR   PATRIC; fig|797304.7.peg.2195; -.
DR   eggNOG; arCOG02942; Archaea.
DR   HOGENOM; CLU_1375506_0_0_2; -.
DR   Proteomes; UP000010468; Chromosome.
DR   Proteomes; UP000011613; Unassembled WGS sequence.
DR   Proteomes; UP000234484; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd09279; RNase_HI_like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   NCBIfam; NF041306; RnaseHI_Halo; 1.
DR   PANTHER; PTHR46387; POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR46387:SF2; RNASE H DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010468}.
FT   DOMAIN          65..195
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
SQ   SEQUENCE   196 AA;  21475 MW;  8A6251879EA59899 CRC64;
     MPVIECDIER ARLRLEEAGV AVESGNTDHE RWRASRGSAT AVAYDDKVVI QGESPQDLEA
     LLRGGGGRAH LYFDGGARGN PGPAAIGWVI VTGDGIVAEG SERIGRATNN QAEYAALIAV
     LEAARDYGYD EVQIRGDSEL IVKQVRGEYD TNNPELREKR VTVHELLSSF DEWAIEHVPR
     EVNERADELA NEAFES
//
DBGET integrated database retrieval system