ID L0DEB7_SINAD Unreviewed; 684 AA.
AC L0DEB7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Sinac_2878 {ECO:0000313|EMBL:AGA27168.1};
OS Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 /
OS MOB10).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Singulisphaera.
OX NCBI_TaxID=886293 {ECO:0000313|EMBL:AGA27168.1, ECO:0000313|Proteomes:UP000010798};
RN [1] {ECO:0000313|EMBL:AGA27168.1, ECO:0000313|Proteomes:UP000010798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10
RC {ECO:0000313|Proteomes:UP000010798};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Tindall B., Pomrenke H., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Singulisphaera acidiphila DSM 18658.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003364; AGA27168.1; -; Genomic_DNA.
DR RefSeq; WP_015246318.1; NZ_JH621478.1.
DR AlphaFoldDB; L0DEB7; -.
DR STRING; 886293.Sinac_2878; -.
DR KEGG; saci:Sinac_2878; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_402188_0_0_0; -.
DR OrthoDB; 231918at2; -.
DR Proteomes; UP000010798; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010798};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 186..228
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 305..358
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 454..670
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 285..315
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..447
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 684 AA; 77439 MW; 10744E9C6BEF7BB9 CRC64;
MPAQSQRKPA YSQDQWGAAL ILGLLWVGFG TASYVILGYP RSLPILVLGA LMLLIAGRVQ
SDSERKRWAA PIHQLARELN AIADDPQRPF ELTYVPELGE VLRALRELKK VWHPIPKSDP
PSSLNLTLSS GEFSSQQLTD SLTRSALLAS LTPGVDSLDV SLSGDFSTTD MVSRLESRTF
RWIESSAAEQ EFLGWELKQL REMSFLEIVH PDDYERARDE LRAAISKGEV HGLVLRIKTA
RGKPKAIEMN VGARYGPDLT VSHLRCHITD VTAKIRAERE LRLRTRELTQ VNEQLRHINR
ELEELKDRYS DLYQNAPAMY FSLDDQGRIL ECNDTLLRTL GYRRDEIISQ SYERLLPEWR
RSIFAARFAD FRLNGKVEIE SQWVMANAET IDVWVSGTTV IGLGGKLLHT RIVAQDVTAR
HRLEAELQEK NDRLAVTIDE LSRKNKEMDE FTYVVSHDLQ EPLRTLIAFS DFLLRDCGDK
LDSNGQEYVR YLVDASRRMR ALIHGLLTLS RAGRVTGDFT TVNLEEVMSF IKADLGELIR
SKGAEVRTTA PLPTLWGDRD RISQLLANLI SNGLKYNQSA APWVEVGTLD DEPGPWLTVY
VRDNGIGIDP QFHTKIFQLF RRLHTREEYE GTGAGLAICS KIVHAHGGRI WIESEPNQGA
TFFISLRRSP PESSMPQTEV THAT
//
