ID   L0GT29_9GAMM            Unreviewed;      1283 AA.
AC   L0GT29;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:AGA89923.1};
GN   ORFNames=Thimo_1120 {ECO:0000313|EMBL:AGA89923.1};
OS   Thioflavicoccus mobilis 8321.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Thioflavicoccus.
OX   NCBI_TaxID=765912 {ECO:0000313|EMBL:AGA89923.1, ECO:0000313|Proteomes:UP000010816};
RN   [1] {ECO:0000313|EMBL:AGA89923.1, ECO:0000313|Proteomes:UP000010816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8321 {ECO:0000313|EMBL:AGA89923.1,
RC   ECO:0000313|Proteomes:UP000010816};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Pagani I., Vogl K., Liu Z., Imhoff J.,
RA   Thiel V., Frigaard N.-U., Bryant D., Woyke T.;
RT   "Complete sequence of chromosome of Thioflavicoccus mobilis 8321.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003051; AGA89923.1; -; Genomic_DNA.
DR   RefSeq; WP_015280068.1; NC_019940.1.
DR   STRING; 765912.Thimo_1120; -.
DR   KEGG; tmb:Thimo_1120; -.
DR   PATRIC; fig|765912.4.peg.1083; -.
DR   eggNOG; COG1100; Bacteria.
DR   eggNOG; COG4886; Bacteria.
DR   HOGENOM; CLU_006821_0_0_6; -.
DR   OrthoDB; 6309115at2; -.
DR   Proteomes; UP000010816; Chromosome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR032171; COR.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR   Pfam; PF16095; COR; 1.
DR   Pfam; PF12799; LRR_4; 2.
DR   Pfam; PF08477; Roc; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010816}.
FT   DOMAIN          1092..1251
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   1283 AA;  139745 MW;  932EBDC6DD7A3C94 CRC64;
     MEENQRQSQQ CFDIAQDRIA AEKAARTGHL NLGNLGLTRL PDALRELDFL EELTLGGVIA
     WGDNVYRRQN DGSLEQINED CHPNQLDAIS TLGFLPCLRR LDCSGAKLSN LGFLAGLTAL
     QYLKCSSTQV ADLTPLAGLT NLQALDCGCT PVTDLTPLAG LTNLRSLDCA YTPVAGLEPL
     ADLTTLKSLD CRHTRVADLA PLAGLTELQF LDCGDTRVAD LEPVASLANL QSLDCGGTRV
     VDLTPLAGLA NLQALDCGFT QVADLAPLAS LTNLQSLDCR SAPVTDLGPL ASLGNLQSLI
     CQFTPVADLA PLAGLTNLLS LNCWNTPVID LAPLASIGNL QSLNCSSTPV ADLASLAGLT
     NLRSLECAGS PVTDLAPLAG LTNLRSLDCE GTPVADLGPL INLTNLRSLD CGFTRVTDLA
     PLAGLTNLQS LICRQTPVAD LAPLAALNNL QSFACGNTRI TDLTPLADLA NMESLDCGET
     PISNLPEAIV WLPRLERLIL MPHPGLTNIP AEVLSQGHGD NCLLRLRTHL TDLGAGAKPL
     QDIKVIVLGN GRVGKTQLCR RLRGKSFVEN ADSTHGISVI SRELSLPGDE TPAVLNLWDF
     GGQDIYHGTH ALFMRTRAVF LLVWSPETEQ GEHTHDGLAL RNQPLPYWLE YIRHLGGVRS
     PVVVVQTRCD SGLGESPNLP VDASFLQTLL ADGRFFKRVT YSAKDDSGRA GLLEALQQAV
     IQLRVVLGRP VIGLSRLAVW EQLRDWRDVD AQEQNPGARH HRLLAFDDFA ELCASAGVRS
     PETFAEVLHN AGMAFYRPRL FDDHLVLDQS WALDAIYAIF TPTGAVCQTL KRLGGRFNRP
     LLDALLWRAR GLSADDQRSL LGMMQTTGIC FLHRRSHNPD ETEYIAPDLL PEGRRGAPPA
     LADELAARWV PITGKPVTGG FRYPFLPPSI GRAVLSNLGG SSGTTALYWR YGLCLYDSES
     RASAVVESLA DADDTTLAST GTTYGGKVRV QVKGKGAKQL LGLLLERLDR LNQDHSWEAE
     PLDPGAQDLR ESTSLARLRL RPPSYIFAAL YTKLDLFARF LVPRGILGAR ATGDTHEPGR
     LMPADPPAMT PDTPEVYVSF AWKQDRAEPL VDELIEGLGQ HGIRVLRDSE QLQPGDRISA
     FMKRLSAGRC VLLVLSDAYL CSPFCMTELH GIWVNARQRE DEFLRRIVPL VQSDAGIGTI
     AGRIEHAARW KAEYERLDRL FRQHGLDVIG VEDFRRFKAI GDFYRHVGDM LSFADDVLVP
     RERPTLSRDR FAMVRDLITR TLA
//