ID L0JX84_9EURY Unreviewed; 660 AA.
AC L0JX84;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=2-oxoacid:acceptor oxidoreductase, alpha subunit {ECO:0000313|EMBL:AGB36724.1};
GN ORFNames=Natoc_0875 {ECO:0000313|EMBL:AGB36724.1};
OS Natronococcus occultus SP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=694430 {ECO:0000313|EMBL:AGB36724.1, ECO:0000313|Proteomes:UP000010878};
RN [1] {ECO:0000313|EMBL:AGB36724.1, ECO:0000313|Proteomes:UP000010878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP4 {ECO:0000313|EMBL:AGB36724.1,
RC ECO:0000313|Proteomes:UP000010878};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Eisen J., Klenk H.-P.,
RA Klenk H.-P.;
RT "FINISHED of Natronococcus occultus SP4, DSM 3396.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003929; AGB36724.1; -; Genomic_DNA.
DR AlphaFoldDB; L0JX84; -.
DR STRING; 694430.Natoc_0875; -.
DR KEGG; nou:Natoc_0875; -.
DR eggNOG; arCOG01606; Archaea.
DR HOGENOM; CLU_017038_1_0_2; -.
DR Proteomes; UP000010878; Chromosome.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010878}.
FT DOMAIN 41..226
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 261..498
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 537..612
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
FT COILED 504..531
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 660 AA; 72758 MW; 8825A938A30EB3F4 CRC64;
MAIYSKGFRH GETKIRIRLA TWPLISMSDD ELIWRVSGGS GDGIDSTSQN FAKALMRSGL
DVFTHRHYPS RIRGGHTYVE IRAAADEVQS RGDGYNFLLA LGDSFARNPQ EEAYYGNEEI
KPLSENLDEL REGGVIVYDE GLLSEDDVEE LELEERAEEN DWHVYPVDLR GLAKEHGREV
MRNTAGIGVT AALLDMDLEH IEDLMSDAMG GDVLESNLEI LHEAYEMVDD DFETTHDLRA
PEGDHDTEQA LLSGSNAIAY GAIDAGCRFI AGYPMTPWTD VFTILSQNFP DMGGVSEQVE
DEIAAAALAV GASHAGVKAM SGSSGGGFAL MSEPLGLAEM TETPVVLIES MRAGPSTGMP
TKPEQADLEH VLYTSQGDSQ RVVFAPGNIE EAYEQTRLAF DIAWDYQIPA IVIYDQKLSG
ENKNVDVDFF DREPSPDLGS TLTEEELKEA AHDASGKFKR FDYKEATDGV ASRSIPGQKG
GRYLATGNEH SPVGHISEDP DNRVFQMERR LEKLEQIRAE LDEERDSTQT YFGPEEADYG
IITWGSSQGA VEEAIERLNE QGHSVKGISV SDMMPFAETE VTEFLESVDE AMVVEMNATA
QFRGLIQKEL GRFGDKMTSL LKFNGNPFEP AEIVEGYEVN LADEDRQPEA QVRIEPAAGD
//
