ID L0KAU3_HALHC Unreviewed; 726 AA.
AC L0KAU3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Beta-xylosidase {ECO:0000313|EMBL:AGB41660.1};
GN OrderedLocusNames=Halha_1723 {ECO:0000313|EMBL:AGB41660.1};
OS Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC Halobacteroides.
OX NCBI_TaxID=748449 {ECO:0000313|EMBL:AGB41660.1, ECO:0000313|Proteomes:UP000010880};
RN [1] {ECO:0000313|Proteomes:UP000010880}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35273 / DSM 5150 / MD-1
RC {ECO:0000313|Proteomes:UP000010880};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Gu W.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Tindall B., Pomrenke H., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "The complete genome of Halobacteroides halobius DSM 5150.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycan metabolism; L-arabinan degradation.
CC {ECO:0000256|ARBA:ARBA00004834}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865}.
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DR EMBL; CP003359; AGB41660.1; -; Genomic_DNA.
DR RefSeq; WP_015327376.1; NC_019978.1.
DR AlphaFoldDB; L0KAU3; -.
DR STRING; 748449.Halha_1723; -.
DR KEGG; hhl:Halha_1723; -.
DR PATRIC; fig|748449.3.peg.1676; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_009397_1_2_9; -.
DR OrthoDB; 273314at2; -.
DR Proteomes; UP000010880; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18832; GH43_GsAbnA-like; 1.
DR Gene3D; 2.40.128.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR032291; Abn2_C.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43301; ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE; 1.
DR PANTHER; PTHR43301:SF3; ARABINOSIDASE-RELATED; 1.
DR Pfam; PF16369; GH43_C; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000010880}.
FT DOMAIN 611..721
FT /note="Extracellular endo-alpha-(1->5)-L-arabinanase C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16369"
FT ACT_SITE 279
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 467
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 414
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 726 AA; 80974 MW; CF4DB3E50E620D4D CRC64;
MNQKRKTLLS LVLSFLLVLS ITPVFVKAMS SGPVEQEQPE QSIETEQADS SGLVAHYTFN
QELTDQTGNF EEGKVVGNRI NEEDGALISY GEGKRDQAAI FDGKSGIRLP DGLISSNVYS
VALWVNPAKI TQFTTTFFGA QAKDQWISIV PNGPIGETML WSGEDWYDAP TGLKIPTDQW
SHLTITVNQG EVKVYLNGQE RFSDSGFPDV FTNQKAKFAL GVNYWDAPFK GKLDDLRVYN
TAIKAERVKK LAKGASKIKE PVENKTRVKL DQNSVAVHDP MIIKDKGTYY VFGSHLGAAK
SDDLIHWKSI SNGFTVDNPI IPNPEQELKE ALEWPEPDAE STWAKSPIKL NGKYYLYFSS
STWGAIRSAI GLAIAKNIEG PYEYQGLVIK SYKKGQENLE GVSHNPNVHP NAIDPQVFFD
DQGKLWMTYG SYAGGIHILE MNSQTGKPYP NQGYGKRILG GNEAPIEGSY IQYNPKTEYY
YLFASFGTLA ADGGYNIRVF RSKNPDGPYT DPQGHNSDYQ GTNELDFVKN NIDGHNWENV
EPYGAKLIGN FLFQESKLGY LSPGHNSAIY DEVKDKMFIV FHSRFPGQGG RHQVRVHQML
MNSRGWPVIT PHVYRGETAR KYSTEQVVGT YQYVNHGHDI QATFGNPGGD INLSKQIELN
ADGSITGTVE GSWKMTGDYR VDITIDGETY HGAFLRQWDR GLKKNVMTFS ALSKQGVTIW
GSEIPE
//
