ID L0KUN5_METHD Unreviewed; 422 AA.
AC L0KUN5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase {ECO:0000313|EMBL:AGB49162.1};
GN OrderedLocusNames=Metho_0920 {ECO:0000313|EMBL:AGB49162.1};
OS Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanomethylovorans.
OX NCBI_TaxID=867904 {ECO:0000313|EMBL:AGB49162.1, ECO:0000313|Proteomes:UP000010866};
RN [1] {ECO:0000313|Proteomes:UP000010866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15978 / NBRC 107637 / DMS1
RC {ECO:0000313|Proteomes:UP000010866};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Methanomethylovorans hollandica DSM
RT 15978.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00009236,
CC ECO:0000256|RuleBase:RU004075}.
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DR EMBL; CP003362; AGB49162.1; -; Genomic_DNA.
DR AlphaFoldDB; L0KUN5; -.
DR STRING; 867904.Metho_0920; -.
DR KEGG; mhz:Metho_0920; -.
DR HOGENOM; CLU_027686_1_1_2; -.
DR Proteomes; UP000010866; Chromosome.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR024169; SP_NH2Trfase/AEP_transaminase.
DR PANTHER; PTHR21152:SF24; ALANINE--GLYOXYLATE AMINOTRANSFERASE 1; 1.
DR PANTHER; PTHR21152; AMINOTRANSFERASE CLASS V; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF000524; SPT; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:AGB49162.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Pyruvate {ECO:0000313|EMBL:AGB49162.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010866};
KW Transferase {ECO:0000313|EMBL:AGB49162.1}.
FT DOMAIN 67..367
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 422 AA; 46351 MW; 413DB55DE32BB633 CRC64;
MKISAFIIYK VYIKQVKSST NRKTYLTARS FYPRFQAIYM NLEDTLLMMP GPVPVAPRVL
RAMSKPMINH RSNAFSDIYD DCRQILADVF NTKNDIFVLS GSGTAAMEAA VGCITNPEDR
IIALENGKFG ERFKNIAKRY GKVEPLAYEW GDSIDLGQLE EKLEEGAKAV TLVHNETSTG
ILNPAKEVGK LAKEYGALFI MDGVTSLGGD LVKVDEWNVD IALVGSQKCL ATPPGLSAVS
VSKKAFEAMD EMERMPYYLD LKAYKKSSEK TLRETPYTPA IPLFYALQEA LHIIKEEGME
ARIKRHCTEA AAVRAAVEAM GIEMLPNLKE HSHYSNTVSA MKAPEGVTGN DIKKDMQARG
VVIAGGQDRL SGKIFRIGNM GNVQPKDILL TVAELEIVLK KRGIVSSVGA GIEAASDVLD
TL
//
