ID   L0KZ68_METHD            Unreviewed;       493 AA.
AC   L0KZ68;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Aminoacyl-histidine dipeptidase {ECO:0000313|EMBL:AGB49279.1};
GN   OrderedLocusNames=Metho_1041 {ECO:0000313|EMBL:AGB49279.1};
OS   Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanomethylovorans.
OX   NCBI_TaxID=867904 {ECO:0000313|EMBL:AGB49279.1, ECO:0000313|Proteomes:UP000010866};
RN   [1] {ECO:0000313|Proteomes:UP000010866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15978 / NBRC 107637 / DMS1
RC   {ECO:0000313|Proteomes:UP000010866};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA   Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P.,
RA   Eisen J.A.;
RT   "Complete sequence of chromosome of Methanomethylovorans hollandica DSM
RT   15978.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003362; AGB49279.1; -; Genomic_DNA.
DR   RefSeq; WP_015324445.1; NC_019977.1.
DR   AlphaFoldDB; L0KZ68; -.
DR   STRING; 867904.Metho_1041; -.
DR   GeneID; 14406850; -.
DR   KEGG; mhz:Metho_1041; -.
DR   HOGENOM; CLU_028526_0_0_2; -.
DR   OrthoDB; 133929at2157; -.
DR   Proteomes; UP000010866; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.630.10; Zn peptidases; 2.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   InterPro; IPR001160; Peptidase_M20C.
DR   NCBIfam; TIGR01893; aa-his-dipept; 1.
DR   PANTHER; PTHR43501; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   PANTHER; PTHR43501:SF1; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF016599; Xaa-His_dipept; 1.
DR   PRINTS; PR00934; XHISDIPTASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010866}.
FT   DOMAIN          206..302
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
SQ   SEQUENCE   493 AA;  53568 MW;  B254BFDB9707EB57 CRC64;
     MDQRTQSILS LFEVISSIPR SSKHEERIAS WLKEWALSHR LSFKSDSVNN VMITVPPSVG
     YESSPTVVIQ GHMDMVCEKA ESSPHDFSCD PIKLIYDGDW LRADGTTLGA DNGIALAMAL
     ELAQDPGIKH PPLELLFTVD EETSMQGASA LAPDLISGQV FLNLDSEEEG VFIAGCAGGV
     TTNIEMELEC VPVPDSYGIC KLVAEGMAGG HSGVDIHEKR ANSNKVLAAA IDRLMRFKDA
     HLKDTHFKDP GILLISADGG KAHNAIPRYS QAILAYPVDS LPQMESTIAQ LESELRPEYA
     EREPGLTLRL EKVHKDDTYK AIAPEITMKL LGLLLDLPCG IVSISSAMPD CVETSCNLAV
     IKTAQDKITI ITSQRSSDMV RLGELTGRIG SMGGSVGGAV HNSEGYPAWK PDMASPLLRK
     CEDVYESTFG EKPEVEVIHA GLECAVIGSK FMDLDMVSFG PTIKNPHSPD ERLYIPSVSR
     TWEFLVALLA SFR
//