ID L0L1I8_METHD Unreviewed; 400 AA.
AC L0L1I8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Exodeoxyribonuclease VII, large subunit {ECO:0000313|EMBL:AGB50149.1};
GN OrderedLocusNames=Metho_1977 {ECO:0000313|EMBL:AGB50149.1};
OS Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanomethylovorans.
OX NCBI_TaxID=867904 {ECO:0000313|EMBL:AGB50149.1, ECO:0000313|Proteomes:UP000010866};
RN [1] {ECO:0000313|Proteomes:UP000010866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15978 / NBRC 107637 / DMS1
RC {ECO:0000313|Proteomes:UP000010866};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Methanomethylovorans hollandica DSM
RT 15978.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003362; AGB50149.1; -; Genomic_DNA.
DR AlphaFoldDB; L0L1I8; -.
DR STRING; 867904.Metho_1977; -.
DR KEGG; mhz:Metho_1977; -.
DR HOGENOM; CLU_023625_3_1_2; -.
DR OrthoDB; 60263at2157; -.
DR Proteomes; UP000010866; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR CDD; cd04489; ExoVII_LU_OBF; 1.
DR HAMAP; MF_00378; Exonuc_7_L; 1.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000010866}.
FT DOMAIN 4..99
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 122..330
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 400 AA; 45092 MW; C6D2821901D444F9 CRC64;
MGIFSVSMLN ETIRSLLVND PRLREVWVRG EISNLKKHSS GHYYFTLKDK GSQISCVSFR
QTNRTLKFDP EDSMAVILYG SVDVYTVRGQ YQLKVLDMRP DGIGEMFRIF EQLKKKLEDE
GLFEQSRKRP IPRFPKRVGI STSPTGAAVH DIINVLGRRY PVHVLLAPCL VQGDAAAQSI
ADSIELLNRA DVDVIIVGRG GGSLEDLWPF NEEIVARAIF NSRIPVVSAV GHETDYTIAD
FTADLRAPTP SAAAELVVPD RVELKRFMDS MLQRLEYAAT RKIADLNSRL DHMYDSLEPD
KLREMIDQRY QRIDELVTAM EKDVKYYLGS REMLLKVLAG RMNAVNPLNT LERGYCIAMS
REVVVKSIGA VQAGSRLDLR VTDGTIICDV IEKVEVEHGR
//
