ID   L1PN31_9FLAO            Unreviewed;       672 AA.
AC   L1PN31;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EKY17138.1};
GN   ORFNames=HMPREF9073_01589 {ECO:0000313|EMBL:EKY17138.1};
OS   Capnocytophaga sp. oral taxon 326 str. F0382.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Capnocytophaga.
OX   NCBI_TaxID=1035193 {ECO:0000313|EMBL:EKY17138.1, ECO:0000313|Proteomes:UP000010441};
RN   [1] {ECO:0000313|EMBL:EKY17138.1, ECO:0000313|Proteomes:UP000010441}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0382 {ECO:0000313|EMBL:EKY17138.1,
RC   ECO:0000313|Proteomes:UP000010441};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKY17138.1}.
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DR   EMBL; AMEU01000111; EKY17138.1; -; Genomic_DNA.
DR   RefSeq; WP_009412954.1; NZ_KB291394.1.
DR   AlphaFoldDB; L1PN31; -.
DR   STRING; 1035193.HMPREF9073_01589; -.
DR   PATRIC; fig|1035193.3.peg.1478; -.
DR   eggNOG; COG0768; Bacteria.
DR   HOGENOM; CLU_009289_6_4_10; -.
DR   OrthoDB; 9804124at2; -.
DR   Proteomes; UP000010441; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR   Gene3D; 3.30.10.20; -; 1.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          610..669
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   672 AA;  74714 MW;  5305F21F586DFECB CRC64;
     MEKSDKKITA RTYFVALVIL LMIIIIAVKL IKIQIEGDEY RAKVDETTLR EADIIPSQGN
     LYSDDGSLLA TSVTRYDIRW DGIAPSKANF NKYVKPLSDS LSKMFGRPSN YYLNLLKKER
     NLKNRYLLIA SNLGYSEYAR IKKFPLFDKG PYKGGIIIEK NIKREYPLGG IAHRSIGYAR
     TDETGYTTRV GLEGAYANYL LGTKGRRLEQ KIAKGQWKLA SGFDIIEPKD GYDVVSTINI
     NIQDIAHHAL LTQLKKYKAQ HGCVIVMEVS TGEIKAISNL ELNKKNDTYA ERYNFAIGEA
     HEPGSVFKLM TVVAAMETRN IDTTYVVDIK DGKQQYYDKT FQDSQHHFTG RISLNKAFSV
     SSNVGMTELV HSLFAKTPSD FTSQLLKMNL NQQLGLPILG EGAPFIPTPR DKLWSGVTLE
     SMAIGYAVKI TPLQSLAFYN AIANGGVMVK PRMIKEVKEW NKAIEKFNVE IINGKICSKQ
     TADKVKGMLA DVVRRSYGSG HRLYSPDFSM AGKTGTARKN YANADASKLS YISSFAGFFP
     VDNPKYSCIV VIHEPDRSVG IYGADVSGPV FKSIAHKIYT NSLLMDTVED VENVSGKTTK
     NYEDYYAKAA KYKTVMPDLT GMNVMDAIAL LENMGLRVKF SGEGKVSSQS VAKGAKVARN
     TIVVLQCGEL TN
//