ID   L1Q1G4_9FLAO            Unreviewed;       728 AA.
AC   L1Q1G4;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Alpha-glucosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9073_00290 {ECO:0000313|EMBL:EKY21819.1};
OS   Capnocytophaga sp. oral taxon 326 str. F0382.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Capnocytophaga.
OX   NCBI_TaxID=1035193 {ECO:0000313|EMBL:EKY21819.1, ECO:0000313|Proteomes:UP000010441};
RN   [1] {ECO:0000313|EMBL:EKY21819.1, ECO:0000313|Proteomes:UP000010441}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0382 {ECO:0000313|EMBL:EKY21819.1,
RC   ECO:0000313|Proteomes:UP000010441};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKY21819.1}.
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DR   EMBL; AMEU01000031; EKY21819.1; -; Genomic_DNA.
DR   RefSeq; WP_009413807.1; NZ_KB291438.1.
DR   AlphaFoldDB; L1Q1G4; -.
DR   STRING; 1035193.HMPREF9073_00290; -.
DR   PATRIC; fig|1035193.3.peg.266; -.
DR   eggNOG; COG3023; Bacteria.
DR   HOGENOM; CLU_011166_2_0_10; -.
DR   OrthoDB; 57532at2; -.
DR   Proteomes; UP000010441; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR029483; GH97_C.
DR   InterPro; IPR019563; GH97_catalytic.
DR   InterPro; IPR029486; GH97_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35803:SF1; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB; 1.
DR   PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR   Pfam; PF14509; GH97_C; 1.
DR   Pfam; PF14508; GH97_N; 1.
DR   Pfam; PF10566; Glyco_hydro_97; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..728
FT                   /note="Alpha-glucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003956357"
FT   DOMAIN          22..304
FT                   /note="Glycosyl-hydrolase 97 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14508"
FT   DOMAIN          309..611
FT                   /note="Glycosyl-hydrolase 97 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF10566"
FT   DOMAIN          614..713
FT                   /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT                   /evidence="ECO:0000259|Pfam:PF14509"
SQ   SEQUENCE   728 AA;  82856 MW;  65004AE3F967CE89 CRC64;
     MRFLTFITIT ILSCATAVAQ ELFSPNKALK LSFSLSAEGT PTYSLFYKGK EVVKPSRLGI
     ELFSSNEVKF GAEITKKEGV NTSLYHNFEV VNTQNTTVDE TWQPVWGESQ NIRNHYNELL
     VSLKQKDTHR EMNLRFRLFD DGLGLRYEFP EQKQMPYFVI KEERTEFAMT GDHQAWWIPG
     DYDTQEYDYQ QSRLSEIRAI NQKGRQANLA QTGFSDTGVQ TALMLKTDDG LYINLHEAAL
     VNYGAMHLNL NDKTFVFQSW ITPDANGAKG YMQTPAQTPW RTVIVSDDAR DILASDITLN
     LNEPCALADT SWIHPMKYVG VWWEMITGMK EWSYTYDVPS VHIGKTDYTT LKPHGKHGAT
     TENVKKYIDF AAENGFDGVL VEGWNIGWED WFGHSKDLVF DFQTPYPDFD IEAIHQYAKS
     KGIKMIMHHE TSSSIRNYER FMDKAYQLMN KYEYPAVKSG YVGNIIPRGE NHYSQWVNNH
     YLYAIKKAAD YRIMVNAHEA VRPTGLCRTY PNLIGNESAR GGEYQAFGGS KPNHVCVLPF
     TRLIGGPMDY TPGVFEMDIS KNNPNNHSHC NATLANQLAL YVTMSSPLQM ASDLPENYRR
     FPDAFQFIKE VALDWSESHY LEAEPGAYIT VARKAKSTRN WFIGNTAGKD FTSKIHFSFL
     EPKTTYVAPI YADAKDANYQ TNPQAYTIQK VLVTNKSKLT LHSVAGGGYA ISLYPLTDKV
     QAKGLKKR
//