ID   L1QFR2_9CLOT            Unreviewed;       281 AA.
AC   L1QFR2;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EKY26432.1};
GN   ORFNames=HMPREF0216_01928 {ECO:0000313|EMBL:EKY26432.1};
OS   Clostridium celatum DSM 1785.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=545697 {ECO:0000313|EMBL:EKY26432.1, ECO:0000313|Proteomes:UP000010420};
RN   [1] {ECO:0000313|EMBL:EKY26432.1, ECO:0000313|Proteomes:UP000010420}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1785 {ECO:0000313|EMBL:EKY26432.1,
RC   ECO:0000313|Proteomes:UP000010420};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKY26432.1}.
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DR   EMBL; AMEZ01000055; EKY26432.1; -; Genomic_DNA.
DR   AlphaFoldDB; L1QFR2; -.
DR   STRING; 545697.HMPREF0216_01928; -.
DR   PATRIC; fig|545697.3.peg.1896; -.
DR   eggNOG; COG0287; Bacteria.
DR   HOGENOM; CLU_055968_2_0_9; -.
DR   Proteomes; UP000010420; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010420}.
FT   DOMAIN          5..281
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   281 AA;  31708 MW;  97864837AB2ED081 CRC64;
     MGDIMRIVIV GLGVIGGSYA MALKEAGYNE VYGIDKNIDT LNKAKALGII KEGYEDGKEI
     VSEADLIVLA VYPDLVKSFI SNNKENFKDN AIITDVTGIK QLFINEVLDI LPDNIDFVFA
     HPMAGREKKG IDYATNTVFK DANFLITVTD KNKIESLELI EELAYKMGFK HVKRICPKYH
     DEMIAFTSQL PHALAVALIN SDIEGRNTGE FIGDSYRDLT RIANINETLW SQLFLGNKEN
     LLQAIYNFEE ELDKIKSCLE NEDKEALREL FIKSSVRREK L
//