ID L2EIU9_9BURK Unreviewed; 510 AA.
AC L2EIU9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:EKZ98828.1};
GN ORFNames=D769_13261 {ECO:0000313|EMBL:EKZ98828.1};
OS Cupriavidus sp. HMR-1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1249621 {ECO:0000313|EMBL:EKZ98828.1, ECO:0000313|Proteomes:UP000010442};
RN [1] {ECO:0000313|EMBL:EKZ98828.1, ECO:0000313|Proteomes:UP000010442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMR-1 {ECO:0000313|EMBL:EKZ98828.1,
RC ECO:0000313|Proteomes:UP000010442};
RX PubMed=23409271;
RA Li L.G., Cai L., Zhang T.;
RT "Genome of Cupriavidus sp. HMR-1, a Heavy Metal-Resistant Bacterium.";
RL Genome Announc. 1:E00202-E00212(2013).
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKZ98828.1}.
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DR EMBL; ANKP01000089; EKZ98828.1; -; Genomic_DNA.
DR RefSeq; WP_008645781.1; NZ_ANKP01000089.1.
DR AlphaFoldDB; L2EIU9; -.
DR PATRIC; fig|1249621.3.peg.2655; -.
DR Proteomes; UP000010442; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Transferase {ECO:0000313|EMBL:EKZ98828.1}.
FT DOMAIN 11..215
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 322..463
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 288
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 378
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 382
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 402
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 510 AA; 55295 MW; AE8BBD6E2E8CF3BF CRC64;
MYRDRIRLAD LQNRIMSADQ AAALIQDGMT VGMSGFTRAG DCKAVPVALA RRAATDPLQI
TLITGASLGN DTDKILAESN VLARRLPFQS DSTLRRKIND GEVMFIDQHL GETVEQLRSG
QIAPVDIAVI EATAITETGG IVPTTSVGNS ASFAMMAKKV IVELNLNMPT GLEGLHDIAF
PVQRPYRQPI PLIAVEQRIG LPYIPVDPSR IAAIVITQRD DSPSNALPPD GETRQIAGHL
NALLDREVRA GRLSTSLQPL QAGIGTIANA VLHGLADSPF HDLTMYSEVL QDSTIALIDA
GKLRFASASS MTLSAPVYRR VLDDIERYKS RLILRPQEIS NHPEILRRLG LITINTALEC
DIYGNVNSTH VGGTHMMNGI GGSGDFARNA YLSVFVTKSV AKDGKISSIV PMVSHVDNSE
HDVDILVTEH GLADLRGLAP RERALQVINN CADPAYRDGL LDYFRRACLR GGQTPHLLEE
AFAWHINYRE QGTMQPQGQL GKAANEALAA
//
