ID   L2GR08_VAVCU            Unreviewed;       495 AA.
AC   L2GR08;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA46086.1};
GN   ORFNames=VCUG_02421 {ECO:0000313|EMBL:ELA46086.1};
OS   Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC   Vavraia.
OX   NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA46086.1, ECO:0000313|Proteomes:UP000011081};
RN   [1] {ECO:0000313|Proteomes:UP000011081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA   McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The genome sequence of Vavraia culicis strain floridensis.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sel-1 family.
CC       {ECO:0000256|ARBA:ARBA00038101}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL877465; ELA46086.1; -; Genomic_DNA.
DR   RefSeq; XP_008075429.1; XM_008077238.1.
DR   AlphaFoldDB; L2GR08; -.
DR   STRING; 948595.L2GR08; -.
DR   GeneID; 19880283; -.
DR   VEuPathDB; MicrosporidiaDB:VCUG_02421; -.
DR   HOGENOM; CLU_041164_0_0_1; -.
DR   InParanoid; L2GR08; -.
DR   OMA; YAYDENT; -.
DR   OrthoDB; 1342992at2759; -.
DR   Proteomes; UP000011081; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR11102:SF147; FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11102; SEL-1-LIKE PROTEIN; 1.
DR   Pfam; PF08238; Sel1; 4.
DR   SMART; SM00671; SEL1; 4.
DR   SUPFAM; SSF81901; HCP-like; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011081};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..495
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003960081"
FT   TRANSMEM        471..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   495 AA;  56815 MW;  2589144C7602BCF1 CRC64;
     MFLFVQLLGA SILENLVLDG KIHEAYENIS QASDPSDLIY VYFLKLLHRE EDANFYLMAA
     ENYSPFFQHI YAHKAFFNFE IAAPVSELAG VYSKVAKGIV TKYLTNRFQF RDKMKFEKIQ
     DIPPVNYLIN LITSGDKKAE ETYINLVLAG QIDPRNEIQN LKRLCETGNA KAMTILGNLY
     LEGYGVQKCL STAMHYFRQG AANGDPLSYN GLGKIFMKEG HKDLNLAKKY FEEAASRGSA
     EGDYNLFMFV RNIYKIEDMG LSYLLRSVKR SYMPALFSYA KRLLTNGETA AAVSHMVPIC
     DFDECIVELQ NRAQKDYQDG QYVPCLYKLL FLCETGSLNS MSNLLYLLKT RKDLVPEQDT
     LFHTYCSKLA QMGQVHHLVD LADTYFYGKG TEQSYTKAFS FYYSAMLYKS ARGSYALSYM
     YENGLGCTRS ITDAMSMLYK AYAYDENTYL LVWYTMIKIY LVVMTRIAYS VRWLIGCALG
     ALLGYLFIFK RRMHK
//