ID L5JNI7_PTEAL Unreviewed; 801 AA.
AC L5JNI7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|EMBL:ELK00890.1};
GN ORFNames=PAL_GLEAN10018338 {ECO:0000313|EMBL:ELK00890.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK00890.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB031155; ELK00890.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JNI7; -.
DR STRING; 9402.L5JNI7; -.
DR eggNOG; KOG4225; Eukaryota.
DR InParanoid; L5JNI7; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 291..350
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 365..426
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 740..801
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 51..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 127..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 89950 MW; 4C80FBB81E61A3A1 CRC64;
MWMETSTSPT HRCTQTMEGL PGESSDILPH GFLLKQEQDE QAVEKQLRKR SRFLFPSSSL
PNDWEPPDKK VDTRKYRAEP KSIYEYQPGK SSVLTNEKMT NLEKDLNLCQ TELEADLEKM
ETLNKAPSAN LSQSSAVSPT PEISSEPPGY IYSSNFHAVK RESDGAPGDL GSLENERQIY
KSVLEGGDIP LQGLSGLKRP SSSASTKDSE SPRHFIPADY LESTEEFIRR RHDDKEKLLA
DQRRLKREQE EADIAARRHT GVIPTHHQFI TNERFGDLLN IDDTAKRKSG SEMRPARAKF
DFKAQTLKEL PLQKGDIVYI YKQIDQNWYE GEHHGRVGIF PRTYIELLPP AEKAQPKKLT
PVQVLEYGEA MAKFNFNGDT QVEMSFRKGE RITLLRQVDE NWYEGRIPGT SRQGIFPITY
VDVIKRPLVK NPVDYIDLPF SSSPSRSATT SPQFPSHSKL IIPAPSSLPH PHRALSPEMH
AVTSEWISLT VGVPGRRSLA LTPPLPPLPE ASLYSTDHLS LLARPSPSLS FRLPHSSWST
PRSVVSPRAL PPPHKAYSLA PGAQASLHVN GDSGVHMPPS GIHQDCFSQP LLGSSDRVIS
ELSDAFSSQG KRQLWREESG QYDRKAEREA GERYPGGPKI SKKSCLKPSD VVRCLSTEQR
LSDLHTPEES RPIKPLGSPF PGREAEQTEL HRGGEQAERK AARSGVSQVS PSDNKSSLII
SQQPQAQQRR VTPDRSQASQ DLFSYQALYS YMPQNDDELE LRDGDIVDVM EKCDDGWFVG
TSRRTRQFGT FPGNYVKPLY L
//
