ID L5JP66_PTEAL Unreviewed; 1441 AA.
AC L5JP66;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Laminin subunit alpha-2 {ECO:0000313|EMBL:ELK00722.1};
GN ORFNames=PAL_GLEAN10018701 {ECO:0000313|EMBL:ELK00722.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK00722.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR EMBL; KB031156; ELK00722.1; -; Genomic_DNA.
DR STRING; 9402.L5JP66; -.
DR eggNOG; KOG1836; Eukaryota.
DR InParanoid; L5JP66; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProt.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR CDD; cd00110; LamG; 4.
DR Gene3D; 2.60.120.200; -; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF67; LAMININ SUBUNIT ALPHA-LIKE PROTEIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00054; Laminin_G_1; 3.
DR Pfam; PF02210; Laminin_G_2; 1.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00282; LamG; 4.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 583..766
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 778..955
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1082..1253
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1258..1438
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 999..1038
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 122..222
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 251..327
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 474..578
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1441 AA; 158352 MW; 58349FD05BC42619 CRC64;
MITAAQLVHV DMKASTVNVC GDECTGLLLG DLARLEQMAT GINLTGPLPA PYKMLYGLEN
MTQELKRAPE RLIQLAEGNL NTLVTEMNEL LTRATKVIAD GEQTGQDAER TNTRADSLGE
FIKELAQDAE AVNEKAIKLN ETLGIQDKAF ERNLQGLQKE IDQMMGELRR KNLDTQKEVA
EDELVAAESL LKKVNKLFGE SREKTEEMEK DLREKLTDYE NKLDDAWDLL REATYKIREA
NRLSTVNQKN MTALEKKKEA IESGKRQTEN TLKEGNDILD EANRLADEIN SVIDYVEDIQ
TKLPPMSEEL KDKIDDLSQE IKDRKLAERV SQAESHAAQL NDSSAVLDGI LDEAKNISFN
ATAAFKAYSN IKDYIDEAEK IAKEAKGLAH EATTLATGPQ GSLKETAKGS LQKSFGILNE
AKKLANDVKE NGDNLNGLKT RLEIADVRNG DLLRALNDTL GKLSAIPNDT VAKLQAIKDK
ARQANDTAKD VLAQIKALHQ NLDGLKKNYN QLADSVAKTN AVVKDPSKNI ADAGATVKNL
EQEADRLTDK LKPIKELEDN LRKNISEIKE LINQARKQAN SIKVSVSSGG DCIRTYKPEI
KKGSYNNIVI NVKTAVADNL LFYLGSAKFI DFLAIEMRKG KVSFLWDVGS GVGRVEYPDL
TIDDSYWYRI EASRTGRNGS ISVRALDGPK ASIVPSTYHS VSPPGYTILD VDANAMLFVG
GLTGKLKKAD AVRVITFTGC MGETYFDSKP IGLWNFREIE GDCKGCTVSP QVEDSEGTIQ
FDGEGYALVS RPIRWYPNIS TVMFKFRTFS SSALLMYLAT RDLKDFMSVE LADGHIKVSY
DLGSGMASVV SNQNHNDGKW KSFTLSRIQK QANISIIDID TNQEENIATS SSGNNFGLDL
KADDKIYFGG LPTLRNLRPE VNLKKYSGCL KDIEISRTPY NILSSPDYVG VIKGCSLENV
YTVSFPKPGF VELPPVPIDV GTEINLSFST KNESGIILLG SGGTPAPPRR KRRQTGQPIS
FKNADIGRCT HQKPHEDEDG AVPAEIVTQP EPVPTPAFPI PTPVLAHGPC AAESEPAFLI
GSKQFGLSKN SHIAIAFDDT KVKNRLTIEF DVRTEAESGL LFYMARINHA DFATVQLKNG
FPYFSYDLGS GDTNTMIPAK INDGQWHQIK IMRIKQEGIL YVDGASNRTI SPKKADILDV
VGMLYVGGLP INYTTRRIGP VTYSIDGCIR NLQMAEASVD LEQPTSSFHV GTCFATAQKG
TYFDGTGFAK AVGGFKVGLD LLVEFEFRTT RATGVLLGIS SQKMDGLGIE MIDEKIMFHV
DNGAGRFTAV YNARIPGHLC DGRWHKVTAN KIKHRIELTV DENQVEAQSP NPASTSADTN
DPVFVGGFPD GLNQFGLTTN IPFRGCIRSL RLTKGTGKPL EVHFAKALEL RGVQPVSCPA
K
//
