ID   L5JYT3_PTEAL            Unreviewed;       967 AA.
AC   L5JYT3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Ninein-like protein {ECO:0000313|EMBL:ELK04475.1};
GN   ORFNames=PAL_GLEAN10002744 {ECO:0000313|EMBL:ELK04475.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK04475.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR   EMBL; KB031070; ELK04475.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5JYT3; -.
DR   STRING; 9402.L5JYT3; -.
DR   eggNOG; ENOG502QUMH; Eukaryota.
DR   InParanoid; L5JYT3; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR18905; NINEIN; 1.
DR   PANTHER; PTHR18905:SF12; NINEIN-LIKE PROTEIN; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 3.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          26..61
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          270..305
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          143..202
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          430..457
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          499..578
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          722..956
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        169..184
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   967 AA;  111209 MW;  FEC64D65EA69309A CRC64;
     MFLASPAKVE LILPTCYGMD EEEENHYVSQ LKEVYSSCDT TGTGFLDREE LTQLCLKLHL
     EKQLPIILQT LLGNDHFARV NFEEFKEGFV AVLSSNAGFG PFDEDSNSLE SGFCTESVYS
     LPENSSITVQ TWTAVPPKYV SGSKWYGRRS QPEPRDSATG AKCLPEQQAR ATVRSQVRRS
     ASLESVESLK SDEEAESAQE PQNDLLETQG QLPTWDSEVF GSPQKSCSPF FDTPESQVRG
     IWEELGVGRS GHLSEQELAV VCQSIGLQGL KKEELEDLFN KLDQDRDGRV SLEEFQLGLS
     NYGPTSLLKS STPVKLSRSW SHHQVLEEGD CHTATTSSLV SMCSGPRLFC SVDNGTGFAF
     PEQLFALWAQ EGIQNGREVL QSLDFSVDEK VNLLELTWAL ENELMMVHGA TQQAALACYR
     QELSFCQGQV EQMARERDKA RKDLEKAEKR NLEFVKEMDD CHLALEQLTE KKIKHLEQGY
     RERLCLLRSE VEMERELFWE QACRQRAALE KDLEHLQAED ASLREKLTLA LKLEPQSIEL
     LAQEERFMEV LKEYELKCRD LQDRSDELQA ALESLQAQLP QSWRSQTNAQ PNGQLFPRHG
     RAGIISFVGD STPVSIETEI MMEQVKEHYQ DLKIQLETKV NYYEREIEVI KRDFAKEKKE
     MEQTFRLEFS VLEDQKADLE SLHVKSQEVI KGLQDQLQSA AHGPELERKF DLERVEMEQR
     YTQALSGLAQ QLAQEKDQLE EELHQRHQHE LQQIRIELDR LSEENMLLKN ELGRIQQELE
     STERTNDAQR KEIEVLKRDK EKACSEVEEL NKQSQKCKDE LTQLNHRVLQ LEEEVSTQQA
     RNEKNCITIQ VLTQRLEEAG CRVELQEEHK KQLKDTEEQV EEMEMILKNL EMLLQEKVSE
     LGEQFEKNTK SDLLLKDLYV ENAHLIKALQ VTEEKQRRAE KKNRILEEKV RALNKLISKI
     TSASLSV
//