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Database: UniProt
Entry: L5K7W2_PTEAL
LinkDB: L5K7W2_PTEAL
Original site: L5K7W2_PTEAL 
ID   L5K7W2_PTEAL            Unreviewed;      1793 AA.
AC   L5K7W2;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   SubName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B {ECO:0000313|EMBL:ELK07437.1};
GN   ORFNames=PAL_GLEAN10012761 {ECO:0000313|EMBL:ELK07437.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Chiroptera; Megachiroptera;
OC   Pteropodidae; Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07437.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y.,
RA   Zhou P., Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y.,
RA   Sun X., Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G.,
RA   Wang L.F., Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the
RT   evolution of flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; KB030979; ELK07437.1; -; Genomic_DNA.
DR   InParanoid; L5K7W2; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014873; VDCC_a1su_IQ.
DR   InterPro; IPR005447; VDCC_N_a1su.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   PANTHER; PTHR10037:SF161; PTHR10037:SF161; 2.
DR   Pfam; PF08763; Ca_chan_IQ; 1.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00167; CACHANNEL.
DR   SMART; SM01062; Ca_chan_IQ; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000010552};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   TRANSMEM     51     68       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     89    110       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    122    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    177    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    254    275       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    287    309       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    438    458       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    464    481       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    563    585       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    642    663       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    870    888       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    908    928       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    940    958       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1001   1023       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1113   1138       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1194   1213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1225   1247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1304   1333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1402   1425       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1441   1476       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED      666    692       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1793 AA;  201401 MW;  10BFE586B26933A2 CRC64;
     MRAGEAWAPD LVTVSPSGGG LAVCCTARCP PWPSPSPPPR RLPVLNPRTP FEYMILATII
     ANCIVLALEQ HLPDGDKTPM SERLDDTEPY FIGVFCFEAG IKIVALGFAL HKGSYLRNGW
     NVMDFVVVLT GILATAGTDF DLRTLRAVRV LRPLKLVSGI PSLQVVLKSI MKAMVPLLQI
     GLLLFFAILM FAIIGLEFYM GKFHKACFPN STDADPTGDF PCGPEPPARL CEGDTQCREY
     WPGPNFGITN FDNILFSVLT VFQCITMEGW TDILYNTNDA AGNTWNWLYF IPLIIIGSFF
     MLNLVLGVLS GEFAKERERV ENRRAFLKLR RQQQIERELN GYLEWIFKAE EVMLAEEDRN
     AEEKSPLDVL KRAATKKSRN DLIHAEEGED RFADLCAGGS PFARAGLKSG KTESSSYFRR
     KEKMLRFLVR RVVKAQSFYW AVLCVVALNT LCVAMVHHNQ PQRLTTALYF AEFVFLGLFL
     TEMSLKMYGL GPRSYFRSSF NCFDFGVIVG SIFEVVWAAI KPGTSFGISV LRALRLLRIF
     KVTKYWNSLR NLVVSLLNSM KSIISLLFLL FLFIVVFALL GMQLFGGQFN FKDETPTTNF
     DTFPAAILTV FQILTGEDWN AVMYHGIESQ GGVSKGMFSS CYFIVLTLFG NYTLLNVFLA
     IAVDNLANAQ ELTKDEEEME EAANQKLALQ KAKEVAEVSP ISAANVSIAA PTHEDVEKEA
     EEKEGETQDR DRDKELRNHH PKEPCGDLGD SGAMAVGPVH SLPSTCPQKA EEQPEDADNQ
     RNVTRMGSQP TDPGAPAHVP AVPTGPPAEG TVVPSGSVDL ESQADGRKEV EADDVTRSGP
     RPIVPYSSMF CLSPTALLRR CCHYIVTMRY FEMVILVVIA LSSIALAAED PVRTDSPRNN
     ALKYLDYIFT GVFTFEMVIK MIDLGLLLHP GAYFRDLWNI LDFIVVSGAL VAFAFSGSKG
     KDINTIKSLR VLRVLRPLKT IKRLPKLKAV FDCVVNSLRN VLNILVVYVL FMFIFAVIAV
     QLFKGKFFYC TDESKERERD CRGQYLDYEK EEVEAQPRQW KKYDFHYDNV LWALLTLFTV
     STGEGWPMVL KHSVDATYEE QGPSPGYRME LSIFYVVYFV VFPFFFVNIF VALIIITFQE
     QGDKVMSECS LEKNERACID FAISAKPLTR HMPRDKQSLQ YKTWTFVVSP PFEYFIMAMI
     ALNTLVLMMK FYGAPYEYEL LLKGLNVAFT SVFSMECLLK IIAFGVLNYF RDAWNVFDFV
     TVLGSITDIL VTEIANNFIN LSFLRLFRAA RLIKLLRQGY TIRILLWTFV QSFKALPYVC
     LLIAMLFFIY AIIGMQVFGN IALDDDSSIN RHNNFRTFLQ ALMLLFRSAT GEAWHEIMLS
     CLSDRACDEH ASASECGSDF AYFYFVSFIF LCSFLMLNLF VAVIMDNFEY LTRDSSILGP
     HHLDEFIRVW AEYDPAACGR ISYSDMFEML KHMSPPLGLG KKCPARVAYK RLVRMNMPIS
     SEDMTVHFTS TLMALIRTAL EIKLAPAGTT QHQCDAELRK EISSVWANLP QKTLDLLVPP
     HKPDEVTVGK VYAALMIFDF YKQSKTSRDQ THQAPGGLTQ MGPVSLFHPL KATLEQTQPA
     VLRGARVFLQ QKSSTSLSNG GAVQTQESGI KESVSWGTQR TQDVPCEARR PLERGHSTEI
     PVVQPRKPAV DVQMQSMTLR GPDGEPQPGL ESQGRAASMP RLAAETQPED TLTFEEAVAT
     NSGRSSRTSY VSSLTSQPHP PRRVPNGYHC TLGPGRGSGA RLSARHPDRD HWC
//
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