ID L5KEF9_PTEAL Unreviewed; 2012 AA.
AC L5KEF9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=CUB and sushi domain-containing protein 1 {ECO:0000313|EMBL:ELK10064.1};
GN ORFNames=PAL_GLEAN10015367 {ECO:0000313|EMBL:ELK10064.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK10064.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; KB030771; ELK10064.1; -; Genomic_DNA.
DR eggNOG; KOG4297; Eukaryota.
DR InParanoid; L5KEF9; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 19.
DR CDD; cd00041; CUB; 5.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 20.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 5.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 5.
DR Pfam; PF00084; Sushi; 19.
DR SMART; SM00032; CCP; 20.
DR SMART; SM00042; CUB; 4.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 20.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 6.
DR PROSITE; PS01180; CUB; 4.
DR PROSITE; PS50923; SUSHI; 18.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1896..1917
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..54
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 56..164
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 167..228
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 230..338
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 344..405
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 407..515
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 580..688
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 775..836
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 886..948
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 949..1010
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1011..1075
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1076..1133
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1134..1191
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1221..1278
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1279..1341
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1342..1399
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1403..1460
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1461..1519
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1520..1579
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1580..1637
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1638..1695
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1696..1755
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1928..1985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1930..1948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1970..1985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1104..1131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1162..1189
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1249..1276
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1312..1339
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1370..1397
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1431..1458
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1490..1517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1608..1635
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1666..1693
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 2012 AA; 215903 MW; 95DBBAF9B3293152 CRC64;
MPQNGSRYGD SREPGDAVTF QCDPGYQLQG QAKITCVQLD SRFFWQPDPP TCIAACGGNL
TGPAGVILSP NYPQPYPPGK ECDWRIQVNP DFVVALKFKS FNMEPSYDFL HVYEGDSSNS
PLIGSFQGAQ APDRIESSGN SLFLAFRSDA SVGLSGFAIE FKEKPREACF DPGNVMNGTR
VGVDFKLGST VTYQCDSGYE AEDPASITCV IGADGKPAWD RALPSCHAPC GGQYTGSEGV
VLSPNYPHNY TAGQTCLYSV TVPKEFVVFG QFAYFQTALN DSAELFDGAH PEARLLSSLS
GSHSGETLPL ATSNQILLRF SAKSGGSARG FHFMYQAVPR TSDTQCSSVP EPRYGRRIGS
EFSAGSIVRF ECNAGYLLQG SAAVRCQAVP SALAQWNDTV PSCVVPCSGN FTQRRGTLLS
PGYPEPYGNN LNCLWRIAVT EGSGIQIQVI SFATEQNWDS LEIYDGGDVT APRLGSFSGT
TVPALLNSTY NKLCLHFQSD ISVSASGFHL EYKTVGLSAC QEPALPSHGI RTGDRYLAND
VLSFQCEAGY TLQVDGTSSP DSGQRWPAAL TALVHSTATC GGTLASMGGV ILSPGFPGAY
PNNLDCVWRI TLPVGYGVHI QFLNFSTEAN HDYLEIQNGP SAGSPLIGQF SGSDLPSALL
STTHETLVRF YSDHSENRPG FKLTYQAYEL QNCPDPPPFQ NGYMINSDYS VGQSVSFECY
PGDGPDQSAP QLGVFSGNTA LETAYSSSSR VLLKFHSDFS NGGFFVLNFH AFQLKRCQPP
PTVLRAEMLA EDEDYEIGDF VRYQCHLGYT LSGADTLTCR LSSQLQFEGT VPTCEGPSGQ
SPLLAVLSGN HSEPSNFTST SNRLFLRWST DHATSKKGFQ IRYAAPYCSL PHALRNGGVL
NRTTGALGSK VHYFCKPGHR MIGPSNATCR RSPTGMFQWD APPPLCQAVS CGIPEAPGNG
SFSGTEFTLD SKVTYECDEG FELEAAQQAA AVCQQDGSWS NGGRPPACKP VTCPGIEAQL
SEHVTWRLVS GSPSEYGAQV LLSCSPGYYL EGGRLVQCQA NGTWSIGEER PRCRVISCGS
LSFPPNGNKI GTLTTYGATA IFTCNTGYTL VGSHVRECLA NGLWSGAETR CLAGHCGSPD
PVVNGHISGD GFSYRDTVVY QCNPGFRLVG TSVRICLQDH KWSGQTPVCV GEHAPDELRG
APRSHRVSVT AQTCSVRTAA ITCGHPGNPA HGLTSGTAFN LNDVVNFTCS SGYVLQGAAR
AQCRSSGQWS SPVPTCRVVN CTDPGFVDNA VRHGQPSPAE SFVYGTSVMY HCEEGFYPLG
SSALSCTATG LWDRSLPRCL AISCGHPGVP ANAVLIGELF TYGATVRYAC RGTQTLVGNS
TRVCQGDSRW SGTLPHCTGH SPGFCGDPGT PAHGSRLGDE FKTKSLLRFS CEVGYQLRGS
PERTCLLNGS WSGLQPACEA VSCGNPGTPA HGMIVSSDGV LFSSSVIYAC WDGYRTSGLT
TRHCTANGTW TGSAPDCTII SCGDPGTLAN GVQFGADFTF NKTVSYQCNP GYVMEPATSP
TIRCTKDGTW NHSKPACRAV LCGPPPPVQN GQVEGTDFRW GSSVSYSCAA GYQLSHSAIL
SCEGRGVWRG DAPQCLAVFC GDPGTPAEGH LSGKSFTYRS EVSFQCKVPF ILVGSSRRTC
QADGTWSGVQ PTCIAHACRQ PETPAHTDVR AIDLPAFGYT LVYTCHPGFF LAGGSEHRTC
KADMKWTGKP PVCKIPADVF FVNSVWKGYY EYLGKRQPAT LTVDWFNATS SKVNATFAEG
PRVQLKLTGV YRREEAHLLL KAFQIRGSVD VFVSKFENDN WGLDGYVSSG LGQGGLTFHG
NVHGRDFGRF KLERQEPSRP GRDPAQQHQG TSSGSVAAAI LVPFFALILA GFVFHLYKHR
TRPKVQYNGY AGHESSNGQA SFENPMYDTS LKPTGPAEQP TRPKVQYNGY AGHESSNGQA
SFENPMYDTS LKPTEAKAVR FDTALNTVCT VV
//
