ID L5KEL3_PTEAL Unreviewed; 451 AA.
AC L5KEL3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=PHD finger protein 10 {ECO:0000256|ARBA:ARBA00016995};
GN ORFNames=PAL_GLEAN10013322 {ECO:0000313|EMBL:ELK09995.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK09995.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SAYP family.
CC {ECO:0000256|ARBA:ARBA00006097}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB030789; ELK09995.1; -; Genomic_DNA.
DR RefSeq; XP_006915111.1; XM_006915049.2.
DR AlphaFoldDB; L5KEL3; -.
DR STRING; 9402.L5KEL3; -.
DR GeneID; 102881131; -.
DR CTD; 55274; -.
DR eggNOG; KOG1512; Eukaryota.
DR InParanoid; L5KEL3; -.
DR OrthoDB; 5490909at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0071564; C:npBAF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd15528; PHD1_PHF10; 1.
DR CDD; cd15529; PHD2_PHF10; 1.
DR CDD; cd21085; WH_NTD_PHF10; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038045; PHF10_PHD_finger_1.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF8; PHD FINGER PROTEIN 10; 1.
DR Pfam; PF00628; PHD; 2.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 330..389
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 386..434
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 240..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 51297 MW; D34959101637DFDF CRC64;
MGSGDSSRSC ETSSQDLGFS YYPAENLIEY KWPPDETGEY YMLQEQVSEY LGVTSFKRKY
PDLERRDLSH KEKLYLRELN VITETQCTLG LTALRSDEVI DLMIKEYPAK HAEYSVILQE
KERQRITDHY KEYSQMQQQN TQKVEASKVP EYIKKAAKKA AEFNSNLNRE RMEERRAYFD
LQTHVIQVPQ GKYRVLPTER TKVSSYPVAL IPGQFQEYYK RYSPDELRYL PLNTALYEPP
LDPELPALDS DGDSDEAEEG RGGERRRAEG TSDSSSGNVS EGEGLPDSQD ESLQGRQRSR
DKAATPRKDA PKRSVLSKSV PGYKPKVIPN ALCGICLKGK ESNKKGKAES LIHCSQCDSS
GHPSCLDMTM ELVSMIKTYP WQCMECKTCI ICGQPHHEEE MMFCDVCDRG YHTFCVGLGA
IPSGRWICDC CQRAPPTPRK MGRRGKNSKE G
//
