ID   L5KGD3_PTEAL            Unreviewed;       945 AA.
AC   L5KGD3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Kinesin-related protein 1 {ECO:0000313|EMBL:ELK10630.1};
GN   ORFNames=PAL_GLEAN10006226 {ECO:0000313|EMBL:ELK10630.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK10630.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KB030717; ELK10630.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5KGD3; -.
DR   STRING; 9402.L5KGD3; -.
DR   eggNOG; KOG0245; Eukaryota.
DR   InParanoid; L5KGD3; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24115:SF344; KINESIN-LIKE PROTEIN KIF28P; 1.
DR   PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR   Pfam; PF12423; KIF1B; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          1..229
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          231..257
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..249
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         79..86
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   945 AA;  106059 MW;  19CDEEA738811F80 CRC64;
     MHSGTTTIQD PKNPEHVKTF TFDLAYWSHS GFQMDKDGVF ISADPNSKFA SQSDVFHDLG
     RAVLDSAWQG YNATLLAYGQ TGSGKSYSMM GSGANKGLVP RVCEELFQAT ETQERNQEHQ
     TPLKGTLSVI EADVFGVNTN KVTFSMLEIY NEQVRDLLSR TKKPGGLKVR EDQQLGFYVE
     GLTSVPCENY VQIERLMEQG TKIRTTASTS MNASSSRSHM VITIQFKQSA PPLLPRAPTA
     PPSTEPRLPA ASPSTPATCC LNPSLPAEQS AHSRAEHGLR TDQLTWAHQL EQAREEWRQH
     YVAIAQERQM MKTVPHLLNV NEDPQLTGVL KHFLQADFRP LGLLSYQLLQ SEALLTIPAP
     QPPTPNPLGT RALGAVCRDR IILGSNSAYL YVGFPWERGG EDLSRFDYDF FQLERAAAEG
     VSVDQLGAGD RGEGKADPSV LVVFQDYVKL MPLVAEANQM SEELKKPTGP QGPQTNIPSQ
     IVLQGGLSGY LGGFYVTKKP LGTRDPITRK LIRDFITPEL KMELKVKNLA SSDSRGCDLQ
     KEVMVKVTNQ RTHEVWIWSK AKFINRKFLM EELYQRFLDG EDSHVVQEDD PFWDPVQVVH
     LGSAHIWLQP LAYCMKFEEQ AEFLNCDGLE EAVLHIHITP CSPAGRACGE EDVVIDPLEL
     LGKRMDFQIR IVRCLGAKWL KEDAERGIQM GYRIYNLPYT LYTKPVWKIM NPQIEESVQF
     TALNASQEFL NYLQTNALIV DLWGLQEGCT ELSCSQLDLL VTDEGHIMVD TKKISTVIDI
     GQTASAQMSE LYLKLLRLEQ ETGMLRSINR ALSEENVLLK ESLEKTGSGQ RAHQPSSTLK
     ITGMTAPSPA ARELDQACTQ RASYDREFAK ALKGFYQSMN VARGKFLKLR CHKPPEDDQM
     LRPFVHQQSQ MLKDFGELLE SSLWKLKNDV ALIVKKKREC LLHSE
//