ID L5KNR4_PTEAL Unreviewed; 626 AA.
AC L5KNR4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Sodium-independent sulfate anion transporter {ECO:0000313|EMBL:ELK12273.1};
GN ORFNames=PAL_GLEAN10014581 {ECO:0000313|EMBL:ELK12273.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12273.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|ARBA:ARBA00008692, ECO:0000256|RuleBase:RU362052}.
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DR EMBL; KB030661; ELK12273.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KNR4; -.
DR STRING; 9402.L5KNR4; -.
DR eggNOG; KOG0236; Eukaryota.
DR InParanoid; L5KNR4; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814:SF55; SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 185..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 222..245
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 324..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 388..406
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 418..448
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 463..547
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 566..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 66341 MW; F213967620E19A2C CRC64;
MAPMSCCCSP AAVRRRLPVL AWLPRYSLQW LKMDLIAGLS VGLTVIPQAL AYAEVAGLPP
QYGLYSAFMG CFVYLILGTS RDVTLGPTAI MSLLVSSYTF HEPAYAVLLA FLSGCIQLAM
GFLCLGFLLD FISCPVIKGF TSAAAITIGF GQVKNLLGLR DAPRQFFLQV YHILRNVGDT
RVGDAGLGLV CMLLLLLLKL MRDHMAPTHS ETPLGVRLSH GLVWTATTAR NALVVSFAAL
VAYSFEVTGH QPFILTGKIV EGLPPVQVPP FSVTTANRTV SFAEMAQDMG AGLAVVPLMG
LLESIAVAKS FASQNNYRVD ANQELLAIGL TNVLGSFVSS YPVTGSFGRT AVNAQSGVCT
PAGGLVTGVL VLLSLGCLTS LFPYIPKAAL AAVIIMAVAP LCDPRIVRTL WRVKRLDLLP
LCVTFLLCFW EVQYGILAGT LVSGLILLHS VARPQMKVSE GPVLVVQPAS GLHFPAVEAL
REAIVSRALE APRPRCAVLD CTHVCSADYT VVLGLAGLLE DFRSHGVTLA FVGLQVPVLR
VLLSADLSHL QHFPTLEEAG GCSRVTGDEL GQPSVPTPCR RRPAGQNPGG REGQTLESES
GELGDDGGTV CALSGPLVAG SWFSGL
//
