ID L5KUV2_PTEAL Unreviewed; 426 AA.
AC L5KUV2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Cytoplasmic dynein 2 light intermediate chain 1 {ECO:0000256|ARBA:ARBA00018863};
GN ORFNames=PAL_GLEAN10021299 {ECO:0000313|EMBL:ELK14746.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK14746.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton, cilium
CC axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton,
CC cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
CC -!- SIMILARITY: Belongs to the dynein light intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00006831}.
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DR EMBL; KB030567; ELK14746.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KUV2; -.
DR STRING; 9402.L5KUV2; -.
DR eggNOG; KOG3929; Eukaryota.
DR InParanoid; L5KUV2; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0035721; P:intraciliary retrograde transport; IEA:InterPro.
DR GO; GO:0035735; P:intraciliary transport involved in cilium assembly; IEA:InterPro.
DR InterPro; IPR040045; DYNC2LI1.
DR InterPro; IPR022780; Dynein_light_int_chain.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13236:SF0; CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1; 1.
DR PANTHER; PTHR13236; DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2; 1.
DR Pfam; PF05783; DLIC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
SQ SEQUENCE 426 AA; 47869 MW; 4B4BC8D51927A9D2 CRC64;
MPRYPLGLTC ARLTFPSIAS PLFHPSLEGV GRERPLRYLW GEESTRDQLV EEVVGLSCLQ
PLAGETLWEI AKAEVEKRGN NGSEGDGVEI GEKSVFFIGS KNGGKTTIIL RCLDRDEPPK
PTLALEYTYG RRAKGHNIPK DIAHFWELGG GTSLLDLISI PITSDTLRTF SIVLVLDLSK
PNDLWPTMEN LLQATKSHVD KVIMKLGKTN SKAASEMRQK IWSNMQKDHQ DRELIDPFPI
PLVIIGSKYD IFQDFDSEKR KVICKTLRFV AHYYGASLMF TSKSEALLLK IRGVINQLAF
GIDKSKSICV DQNKPLFITA GLDSLSHIGS PPVPDNDIGK LHAHSPMELW KKVYAKLFPP
KTVNTLKDIK DPAKDPQYAE SEVDEMRIQK DQFSPFLQFF ILTLKKIIEY SVPVVIIPHL
STILLM
//
