ID L5KXW2_PTEAL Unreviewed; 327 AA.
AC L5KXW2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN ORFNames=PAL_GLEAN10000411 {ECO:0000313|EMBL:ELK15831.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK15831.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- FUNCTION: Putative odorant or sperm cell receptor.
CC {ECO:0000256|ARBA:ARBA00003929}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; KB030505; ELK15831.1; -; Genomic_DNA.
DR RefSeq; XP_006908388.1; XM_006908326.1.
DR AlphaFoldDB; L5KXW2; -.
DR STRING; 9402.L5KXW2; -.
DR GeneID; 102886811; -.
DR KEGG; pale:102886811; -.
DR eggNOG; ENOG502SMFV; Eukaryota.
DR InParanoid; L5KXW2; -.
DR OrthoDB; 5254491at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR CDD; cd15417; 7tmA_OR5A1-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26452; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26452:SF354; OLFACTORY RECEPTOR 5A1; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:ELK15831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 28..51
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 63..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 203..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 241..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 275..293
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 44..293
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 327 AA; 36262 MW; 3E0211CD5699041E CRC64;
MFTAKAWNSS SVTEFILLGF ADHPELQAFL FVTFLGIYLV TLAWNLALVF LIRGDTHLHT
PMYFFLSNLS FIDISYSSTV APKMLTDFFQ AQKTIPFWGC AAQFFFFIGL GLTECFLLTA
MAYDRYAAIS SPLLYAAIMS QGLCARMVLG AYVGGFLSSL VQASSIFRLH FCGPNVINHF
FCDLPPVLAL SCSDIFLSQV VNFLVVATVG GTSSLILLVS YGYIAAAVLK IRSAEGRRKA
FNTCAAHLMV VALLFGTALF MYLRPSSSYS LGRDKVVSVF YTLVTPMLNP LIYSWRNKEI
KEALGKVLER KKAFSQFRSK SISSQTT
//
