ID L5L3I7_PTEAL Unreviewed; 401 AA.
AC L5L3I7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Putative leucine-twenty homeobox {ECO:0000313|EMBL:ELK18207.1};
GN ORFNames=PAL_GLEAN10001506 {ECO:0000313|EMBL:ELK18207.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK18207.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; KB030334; ELK18207.1; -; Genomic_DNA.
DR AlphaFoldDB; L5L3I7; -.
DR STRING; 9402.L5L3I7; -.
DR InParanoid; L5L3I7; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR45793; HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR45793:SF18; PAIRED-LIKE HOMEODOMAIN TRANSCRIPTION FACTOR LEUTX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 221..281
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 223..282
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 42..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 44822 MW; A4F72D7605DA1FA6 CRC64;
MKDSCFPGNG PGFLSLGRPH RPHEAGLGRQ VLLEFISEAL TDATQPPQQP HEDSFGVEDR
PVGKPVSYHD SSTLTVNSDT KRRHTDPEGE PIILRRTTTF QEPEFFGSSQ TSPNQTDWGG
TTGDEGGVGR RKGRVSATRC GAGRRISPKR SRGASLRVPP GAVTQSTPFA ASFRCLSCLL
VLSDNPVIFT LLSRVKFLNI LSHFGFLDFL SFSSTLREKP RSARRHRTTF SPKQLRILKE
TFEKTMYPHW FIITALTTVI HLDESVIKTW FKNQRIKRRK QQQLQTRPLL PLEAPNQTIS
VKEEETPSPV ASTDTHPVSE ARDRDPPKAP GIEQPGGAGA SAWNASWDSQ PHDLQEMCLE
ASDIPWATMP YDIDQFIRFY ALPGDDHPNS LDQYLFPKQP G
//
