ID   L5LI28_MYODS            Unreviewed;       731 AA.
AC   L5LI28;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Myosin-X {ECO:0000313|EMBL:ELK25867.1};
GN   ORFNames=MDA_GLEAN10024052 {ECO:0000313|EMBL:ELK25867.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK25867.1, ECO:0000313|Proteomes:UP000010556};
RN   [1] {ECO:0000313|Proteomes:UP000010556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC       {ECO:0000256|ARBA:ARBA00004544}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR   EMBL; KB111427; ELK25867.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5LI28; -.
DR   Proteomes; UP000010556; Unassembled WGS sequence.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.820; -; 1.
DR   Gene3D; 1.20.58.530; -; 1.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR001609; Myosin_head_motor_dom.
DR   InterPro; IPR040640; MyoX_N_SH3.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46049; AGAP003327-PA; 1.
DR   PANTHER; PTHR46049:SF2; UNCONVENTIONAL MYOSIN-X; 1.
DR   Pfam; PF00063; Myosin_head; 1.
DR   Pfam; PF18597; SH3_19; 1.
DR   PRINTS; PR00193; MYOSINHEAVY.
DR   SMART; SM00242; MYSc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW   ProRule:PRU00782};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT   DOMAIN          71..639
FT                   /note="Myosin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS51456"
FT   REGION          615..637
FT                   /note="Actin-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT   BINDING         165..172
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ   SEQUENCE   731 AA;  83329 MW;  EFE14732D373DCFF CRC64;
     MQSKCIIKFC LFCLQGTRVW LRENGQHFPS TVNSCAEGVV VFQTDYGQVF TYKQSTITHQ
     KVTVMHPMNE EGVEDMATLT ELHGGSIMHN LHQRYKRDQI YTYIGSIIAS LNPYKPIAGL
     YERATMERYS KSHLGELPPH VFAVANECYR CLWKRHDNQC VLISGESGAG KTESTKLILK
     FLSVISQQSL ELSLKEKTSC VEQAILESSP IMEAFGNAKT VYNNNSSRFG KFVQLNICQK
     GNIQGGRINR VVRQNPRERN YHIFYALLAG LEGKQREEFY LSVPENYHYL NQSGCVEDKT
     ISDQESFREV ITAMDVMQFS KEEVREVLRL LAGILHLGNI EFITAGGAQV SFKTALGRSA
     ELLGLDPAQL TDALTQRSMI LRGEEILTPL MDSRDSLAMA LYARCFEWVI KKINSRIKGK
     DDFKSIGILD IFGFENFEVN HFEQFNINYA NEKLQEYFNK HIFSLEQLEY SREGLVWEDI
     DWIDNGECLD LIEKKLGLLA LINEESHFPQ ATDSTLLEKL HNQHANNHFY VKPRVAVNNF
     GVKHYAGEVQ YDVRGILEKN RDTFRDDLLN LLRESRFDFI YDLFEHVSSR NSQDTLKCGS
     KHRRPTVSSQ FKDSLHSLMA TLSASNPFFV RCVKPNMQKI EKTVTSTALQ SLPCAYLPPA
     AWLRVQDVLC AQYMLDPVAH KRALERCSWL LVRTANDAAI YGGQTLKGGP ETQEVYPLQS
     CSFSLPCALY G
//