ID L5LSL8_MYODS Unreviewed; 738 AA.
AC L5LSL8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=ADAMTS-like protein 5 {ECO:0000313|EMBL:ELK29449.1};
GN ORFNames=MDA_GLEAN10011510 {ECO:0000313|EMBL:ELK29449.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK29449.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB108036; ELK29449.1; -; Genomic_DNA.
DR AlphaFoldDB; L5LSL8; -.
DR eggNOG; KOG2113; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR CDD; cd03523; NTR_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR047226; KH-I_MEX3_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR047227; MEX3.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23285:SF3; RNA-BINDING PROTEIN MEX3D; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF01759; NTR; 1.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00322; KH; 2.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50189; NTR; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 617..736
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 264..298
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 268..303
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 279..288
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 738 AA; 80728 MW; 1BE9D63124D858B3 CRC64;
MEPTSWPGPS SWCPRQADLG RGPGPHHVPL PPNPGCKIKA LRAKTNTYIK TPVRGEEPVF
IVTGRQEDVE MAKREILSAA EHFSVIRATR SKAGGLPGTA QGPPNLPGQT TIQVRVPYRV
VGLVVGPKGA TIKRIQQRTH TYIVTPGRDK EPVFAVTGMP ENVDRAREEI EAHITLRTGA
FTDAGPDSDF HANGTDVCLD LLGAAAGLWA KAPNPGRRPT LPSASLRGDS TLGTPGGPEA
FYPSSRGGPP GPGEWTPWGS WSHCSSSCGQ GLSVRSRRCV RFPREELCWG DTHEYRLCQL
PDCPPGAMPF RDLQCALYNG HPVLGPQKTY QWVPFYGAPN QCDLNCLAVG HAFYHSFGRV
LDGTPCSWGS RGLCVAGRCL NAGCDGLMGS DAREDHCGRC GGTNDSCLFV QRVFRDTGAF
AGYWNVTLIP EGARHIYAVH RSRNHLGTAE VPRGRRPPGR LDEAARLRPE EGDAVSGRWR
GGFRGAWADP SLAALMGGDG RYVLNGNGEV SPSGTYEAAG TRVVYTRAAW PEETLRAAGP
TSQDLLLQVL LQEPNPGIEF EFWLPRERYG PFQEQAQALG WSLRQPQPLE VEPQSLEPQE
ALAAFPTQTP KPTPDPCPPC PDTRGRAHRL LHLCGSDFVF RARVLGHLRQ AQETRYEVRV
QLVYKNRSPL QSLEYVWAPG RCPCPPMALH REYLLAAQRL VNPDGTQDRL LLPHAGYARP
WSPAEDSRVR LAARHCPV
//
