ID L5LTY5_MYODS Unreviewed; 611 AA.
AC L5LTY5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
GN ORFNames=MDA_GLEAN10005681 {ECO:0000313|EMBL:ELK29512.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK29512.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR EMBL; KB107978; ELK29512.1; -; Genomic_DNA.
DR AlphaFoldDB; L5LTY5; -.
DR eggNOG; KOG2549; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:ELK29512.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:ELK29512.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..78
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 139..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 65281 MW; 8CE3A25BA7B1A30E CRC64;
MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEVSYRIKEI AQDALKFMHM
GKRQKLTTSD IDYALKLKNV EPLYGFHAQE FIPFRFASGG GRELYFYEEK EVDLSDIINT
PLPRVPLDVC LKAPKEQQKA EATEPLKSAK PGQEEDGPLK SKGQGAAPAD GKGEALQSIA
TDPGLYQMLP RFSTFISEGV RVNVVQNNLA LLIYLMRMVK ALMDNPTLYL EKYVHELIPA
VMTCIVSRQL CLRPDVDNHW ALRDFAARLV AQICKHFSTT TNNIQSRITK TFTKSWVDEK
TPWTTRYGSI AGLAELGHDV IKTLILPRLQ QEGDRFRSVL DGPVLSNIDR IGADHVQSLL
LKHCAPVLAK LRPPPDNQDA YRAEFGSLGP LLCSHVVKAR AQAALQAQQV NRTTLTITQP
RPTLTLSQAP QPGPRTPGLL KVPGSIALPV QTLVSARAAA PPQPSPPPTK FIVMSSSSSA
SSTQQVLSLS TSAPGSGSTT TSPVTTTVPS VQPIVKLVST ATAAPPSTAP SGPGSVQKYI
VVSLPPTGDS KGGPTSHPSP VPPQSSAPSP LGGSALCGGK QEAGDSPPPA PGTPKANGSQ
PPGSGSPQPA P
//
