ID   L5LU75_MYODS            Unreviewed;      2238 AA.
AC   L5LU75;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Integrator complex subunit 1 {ECO:0000313|EMBL:ELK29003.1};
GN   ORFNames=MDA_GLEAN10021509 {ECO:0000313|EMBL:ELK29003.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK29003.1, ECO:0000313|Proteomes:UP000010556};
RN   [1] {ECO:0000313|Proteomes:UP000010556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB108645; ELK29003.1; -; Genomic_DNA.
DR   eggNOG; KOG4596; Eukaryota.
DR   Proteomes; UP000010556; Unassembled WGS sequence.
DR   GO; GO:0032039; C:integrator complex; IEA:InterPro.
DR   GO; GO:0034474; P:U2 snRNA 3'-end processing; IEA:InterPro.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR022145; DUF3677.
DR   InterPro; IPR038902; INTS1.
DR   PANTHER; PTHR21224:SF1; INTEGRATOR COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR21224; UNCHARACTERIZED; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF12432; DUF3677; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT   DOMAIN          1854..1972
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          326..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          924..943
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1226..1264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1979..2213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2087..2104
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2136..2151
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2238 AA;  247811 MW;  EE1A0C490DBAE56B CRC64;
     MPRXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
     XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
     XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX EAAVAEKQNA
     PPSIKEPSVV PIEVPPPALL DEIEAAELEG NDDRIEGVLC GAVKQLRATR AKPDSALCLS
     LMYLAKTKPN IFATEGVIEA KGNSLVSVLA CSLLMAAYEE DENWPEIFVK VYIEDSLGER
     IWVDSPHCKA FVDNIQTAFN TRMPPKSMLL QGEAGRSGGD LSAGSSPHPS LTEEEDSQTE
     LLIAEEKLSP EQEGQLMPRY EDLAESVEEY VLDMLRDQLN RRQPIDNVSR NLLRLLTSTC
     GYKEVRLMTV QKLEMWLQNP KILYTVLQHS AELAPKFLAM VFQDLLTNKD DYLRASRALL
     REIIKQTKHE INFQAFCLGL MQERKEPQYL DMEFKERFVV HITDVLAVSM MLGITAQVKE
     AGIAWDKGEK KNLEVLRSFQ NQIAAIQRDA VWWLHTVVPS ISKMAPKDYV HCLHKVLFTE
     QPETYYKWDN WPPESDRNFF LRLCSEVPIL EDTLMRILVI GLSRELPLGP ADAMELADHL
     VKRAAAVQAX XXXXXXXXXX XXRPPGALTQ VSSPCPLCCY PQQPCPLARP AQAPPNVEVL
     KVERVQLLDA VLNLCTYHHP ENIQLPPGQQ PPNLAISTLY WKAWPLLLVV AAFNPENIGL
     AAWEEYPTLK MLMEMVMTNN YSYPPCTLTD EETRTEMLSR ELQTSQREKQ EILAFEGHLA
     AASTKQTITE SSSLLLSQLT SLDPQYKQQQ LLGRLQDLLL GPKADEQTTC EVLDYFLRRL
     GSSQVASRVL AMKGLSLVLS EGSLRDRDGE EKEPPAEEDS GDAETLQGYQ WLLRDLPRLP
     LFHSVSASTA LALQQAVHME TDPQTVSAYL VYLSQHTPVE EQGPHSDLAL DVARLIVERS
     TIMSHLFSKR SCSAESDAVL AALLSIFSRY VRRMRKSKEG EEVYSWSESQ DQVFLRWSSG
     ETATMHILVV HAMVILLTLG PPRAGDEEFL ALLDIWFPDK KPLPTAFLVD TSEEALLLPD
     WLKLRMIRSE VPRLVDAALQ DLEPQQLLLF VQSFGIPVSS MSKLLLHLDQ AVAHDPQTLE
     QNIMDKNYMA HLVEVQHERG ASGGQTFHSL LTASLPPRRD SAEAPKPKSS PEPPPGQGRI
     RASTQVRVLG PEDDLASVFL QVFPLSPGPR WQLSSARPVA LALQQALGQE LARAGTWGAL
     TGAGTVSPAT AWAALSGVAM CPVVPQRCMP QDSGFSSLFL QVLMQMLQWL DSPGVEAGPL
     QAQLKLFATQ YSAQRRISDV RSGFLHLAEA LAFRGDMEVV SSTVRALVAT LKAGEKCGVE
     PELISKVLRG LIRVRSPHLE ELLTALFSAA TALPASRPVA VVSSLLLQEE EPLAAGQQDT
     DGSSCPDLQQ RLLFSRSKGK GQPGPQVPSF RPYLLALLTH QSNWSTLHQC IRVLLGKNRE
     HRFDPSASLD FLWACIHVPR IWQGRDQRTP QAGHGEHPPA GWGDTCASPL VHPGWLTGCP
     LQKRREELAL QLDVLTHRFI TLLADTSDSR ASESRVADAN MACRKLAVAH PLLLLRHLPM
     IAALLHGRTH LNFQEFRQQN HLTFFLHVLG VLELLQPQVF QSEHQGALWD CLRSFIRLLL
     NYRKSSRHLA PFLNKFVQFT HKYITCNAPA AAAFLQKHAD ALHDLSFDSS DLVMLKSLLA
     GLSLPSRDGR ADHGLDEEGE DESSAGSLPL VSVSLFTPLT AAEMAPYMKR LSRGQTVEDL
     LEVLGDIDEM SRRRPEILGF FSTNLQRLMS SEEEACRSLA FSLALRSIQN NPRDFDALRK
     ENVYENNQLA FRVAEEQLGI PALLEAEDMV ALKVPDRLSI LTYVSQYYNY FHGRSPIGGM
     AGVKRSPSEA EEEPSGKKAS PTPARGLPLS PVSTNTMVQR KDRGAEGPPL KAASGAPSTG
     LASRAPAAAD APSEADRREQ ALSCLRKALP GFGGAQAPGR AAHGSRVATD QEGERGRPGR
     ATALHRLGRE GQGPSAGSQK DQVDRPAAWR SHLKPVAKKQ PAERAPELME PRVLGEPRAG
     AVPQKVPGSS EGGVCITLTP VRPNRTPGPA GPQSSLSEAL KSPQDRQREQ DLLTQYVSTV
     NDRSDIIDFL VQKLPQSY
//