ID L5MFN8_MYODS Unreviewed; 647 AA.
AC L5MFN8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Protein fem-1 like protein A {ECO:0000313|EMBL:ELK37434.1};
GN ORFNames=MDA_GLEAN10011090 {ECO:0000313|EMBL:ELK37434.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK37434.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the fem-1 family.
CC {ECO:0000256|ARBA:ARBA00038500}.
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DR EMBL; KB100339; ELK37434.1; -; Genomic_DNA.
DR AlphaFoldDB; L5MFN8; -.
DR eggNOG; KOG0508; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24173; ANKYRIN REPEAT CONTAINING; 1.
DR PANTHER; PTHR24173:SF74; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR Pfam; PF12796; Ank_2; 4.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT REPEAT 67..99
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 134..166
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 167..199
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 199..221
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 512..557
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 558..590
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 647 AA; 71392 MW; A7267EDC67C5B010 CRC64;
MDLRTVVYNA ARDGKLQLLQ KLLSGRSQEE LDELTGEVAG EGTPLLIASR YGHLDVVEYL
VDRCGASGAP PLWAASAAGH LDVVQSLLRR GASVNRTTRT NSTPLRAACF DGHLEVVRYL
VGEHQADLEV ANRHGHTCLM ISCYKGHREI ARYLLEQGAQ VNRRSAKGNT ALHDCAESGS
LEILQLLLGC NARMERDGYG MTPLLAASVT GHTNIVEYLI QEQPAGMEVQ PGPAPEGPSG
LGCVKSQGAS CCPSSPEEPL SETYESCCPT SREAAVEALE LLGATYVDKK RDLLGALKHW
RRAMELRHQG GEYLPKPEPP QLVLAYDYSR EVNTAEELEA LITDPDEMRM QALLIRERIL
GPSHPDTSYY IRYRGAVYAD SGNFERCIRL WKYALDMQQN NLEPLSPMTA SSFLSFAELF
SYVLQDRAAK GSLGTQIGFA DLMGVLCKGV REVERALQLP KEPGDSVQFT KALAIILHLL
YLLEKVECTP DQEHLKHQTV YRLLKCAPRG KNGFTPLHMA VDKDTTNVGR YPVGRFPSLQ
VVKVLLDCGA DPDSRDFDNN TPLHIAAQNS CPGIMNALIE AGAHMDATNA FKKTAYELLD
EKLLAKSTIQ PFNYVTLQCL AARTLDKNKI PYKGFIPEEL EAFIELH
//
