ID L5MI96_MYODS Unreviewed; 367 AA.
AC L5MI96;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Complement C1q tumor necrosis factor-related protein 1 {ECO:0000313|EMBL:ELK38017.1};
GN ORFNames=MDA_GLEAN10004937 {ECO:0000313|EMBL:ELK38017.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK38017.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB099688; ELK38017.1; -; Genomic_DNA.
DR AlphaFoldDB; L5MI96; -.
DR eggNOG; ENOG502QT5D; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR22923; CEREBELLIN-RELATED; 1.
DR PANTHER; PTHR22923:SF63; COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 1; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..45
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 46..367
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003971267"
FT DOMAIN 227..367
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 48..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 40445 MW; C484CB605B079E87 CRC64;
MSYEMGVGVG DPVMPERGGT MGSLGPGHVV ACCLLLAFAC GPVLGRVPPD PEEQQEQEGT
EEPLLDHAER RRGSRPTAGT VRAERGGTMG SLGPGHVVAC CLLLAFACGP VLGRVPPDPE
EQQEQEGTEE PLLDHAERAE DKHGKYSPRE DEEPPASRCY RCCDPGAPLY PTVPVPQINI
TILKGEKGDR GYRGMQGKYG KTGAAGARGH AGPKGQKGSM GAPGDRCKNH YAAFSVGRKK
PLHSNDYYQT VIFDTEFVNL YGHFNMFTGK FYCYVPGVYF FSLNVHTWNQ KETYLHVMRN
AEEVVILYAQ VSDRSIMQSQ SLMLALREQD EVWVRLFKGE RENAVFSDEF DTYITFSGYL
VKPEAEP
//
